Complement Activation in Malaria Immunity and Pathogenesis

Editors: Stoute, José A. (Ed.)

  • Unique resource that addresses the role of complement in malaria
  • Written by experts from leading laboratories
  • Important reference tool for malaria and complement researchers and immunologists alike
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eBook £87.50
price for United Kingdom (gross)
  • ISBN 978-3-319-77258-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £109.99
price for United Kingdom (gross)
  • ISBN 978-3-319-77257-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. 

About the authors

José A. Stoute, M.D.

Professor of Medicine, and Microbiology & Immunology

The Pennsylvania State University Hershey Medical Center and College of Medicine

Table of contents (8 chapters)

  • The Complement System

    Biryukov, Sergei (et al.)

    Pages 1-29

  • Mechanisms of Complement Activation in Malaria

    Taylor, Ronald P. (et al.)

    Pages 31-49

  • Role of Complement in Severe Malarial Anemia

    Stoute, José A.

    Pages 51-64

  • Role of Complement in Cerebral Malaria

    Schein, Theresa N. (et al.)

    Pages 65-90

  • Complement and Malaria in Pregnancy

    Weckman, Andrea (et al.)

    Pages 91-105

Buy this book

eBook £87.50
price for United Kingdom (gross)
  • ISBN 978-3-319-77258-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £109.99
price for United Kingdom (gross)
  • ISBN 978-3-319-77257-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Complement Activation in Malaria Immunity and Pathogenesis
Editors
  • José A. Stoute
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG, part of Springer Nature
eBook ISBN
978-3-319-77258-5
DOI
10.1007/978-3-319-77258-5
Hardcover ISBN
978-3-319-77257-8
Edition Number
1
Number of Pages
XII, 149
Number of Illustrations and Tables
5 b/w illustrations, 17 illustrations in colour
Topics