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Amorphous Drugs

Benefits and Challenges

Authors: Rams-Baron, M., Jachowicz, R., Boldyreva, E., Zhou, D., Jamroz, W., Paluch, M.

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  • Offers a comprehensive review on fundamental concepts and recent advances in the field of amorphous pharmaceuticals
  • World-leading specialists from different fields present their perspectives on amorphous drugs
  • Introduces to both fundamental physical aspects and preparation and formulation methods
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eBook £79.50
price for United Kingdom (gross)
  • ISBN 978-3-319-72002-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £101.00
price for United Kingdom (gross)
  • ISBN 978-3-319-72001-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover £99.99
price for United Kingdom (gross)
  • ISBN 978-3-319-89129-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. 

Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

About the authors

Dr. Marzena Rams-Baron holds an assistant professor position in the Department of Biophysics and Molecular Physics at University of Silesia in Katowice.

Prof. Dr. Renata Jachowicz is currently head of the Chair and Department of Pharmaceutical Technology and Biopharmaceutics at Jagiellonian University in Cracow. She is a member of Committee on Therapy and Drug Research of the Polish Academy of Science, Head of Subcommittee of Pharmaceutical Technology and Biopharmacy and also Head of the Expert Group of Pharmaceutical Technology and Galens Products of Polish Pharmacopoeia Committee.

Prof. Dr. Elena Boldyreva is a Chief Researcher at the Institute of Solid State Chemistry and Mechanochemistry, Siberian Branch of Russian Academy of Sciences in Novosibirsk and the Head of the Chair of Solid State Chemistry of Novosibirsk State University.

Dr. Deliang Zhou  is a principal research pharmaceutical scientist in Drug Products, Operations Science & Technology at AbbVie. 

Dr. Witold Jamróz holds an assistant professor position in the Department of Pharmaceutical Technology and Biopharmaceutics at Jagiellonian University in Cracow

Prof. Dr. Marian Paluch is currently the head of the Department of Biophysics and Molecular Physics at University of Silesia in Katowice. Since 2010 he is an academic editor in AIP Advances. He is (co)author of more than 380 publications, a book and several book chapters. His papers were cited more than 7700 times.

Table of contents (6 chapters)

Table of contents (6 chapters)

Buy this book

eBook £79.50
price for United Kingdom (gross)
  • ISBN 978-3-319-72002-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £101.00
price for United Kingdom (gross)
  • ISBN 978-3-319-72001-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover £99.99
price for United Kingdom (gross)
  • ISBN 978-3-319-89129-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Amorphous Drugs
Book Subtitle
Benefits and Challenges
Authors
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-72002-9
DOI
10.1007/978-3-319-72002-9
Hardcover ISBN
978-3-319-72001-2
Softcover ISBN
978-3-319-89129-3
Edition Number
1
Number of Pages
IX, 230
Number of Illustrations
21 b/w illustrations, 48 illustrations in colour
Topics