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Studies in Mechanobiology, Tissue Engineering and Biomaterials

Biomechanics: Trends in Modeling and Simulation

Editors: Holzapfel, Gerhard A., Ogden, Ray W. (Eds.)

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  • Presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues
  • Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues
  • The essential ingredients of continuum mechanics are provided
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eBook £103.50
price for United Kingdom (gross)
  • ISBN 978-3-319-41475-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £129.99
price for United Kingdom (gross)
Softcover £129.99
price for United Kingdom (gross)
About this book

The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues.
The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Mixture Theory for Modeling Biological Tissues: Illustrations from Articular Cartilage

    Pages 1-51

    Ateshian, Gerard A.

  • A Bio-chemo-mechanical Model for Cell Contractility, Adhesion, Signaling, and Stress-Fiber Remodeling

    Pages 53-81

    McMeeking, Robert M. (et al.)

  • Nonlinear Continuum Mechanics and Modeling the Elasticity of Soft Biological Tissues with a Focus on Artery Walls

    Pages 83-156

    Ogden, Ray W.

  • Microstructure and Mechanics of Human Aortas in Health and Disease

    Pages 157-192

    Holzapfel, Gerhard A.

  • Arterial and Atherosclerotic Plaque Biomechanics with Application to Stent Angioplasty Modeling

    Pages 193-231

    O’Reilly, Brían L. (et al.)

Buy this book

eBook £103.50
price for United Kingdom (gross)
  • ISBN 978-3-319-41475-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £129.99
price for United Kingdom (gross)
Softcover £129.99
price for United Kingdom (gross)
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Bibliographic Information

Bibliographic Information
Book Title
Biomechanics: Trends in Modeling and Simulation
Editors
  • Gerhard A. Holzapfel
  • Ray W. Ogden
Series Title
Studies in Mechanobiology, Tissue Engineering and Biomaterials
Series Volume
20
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-41475-1
DOI
10.1007/978-3-319-41475-1
Hardcover ISBN
978-3-319-41473-7
Softcover ISBN
978-3-319-82364-5
Series ISSN
1868-2006
Edition Number
1
Number of Pages
IX, 316
Number of Illustrations
66 b/w illustrations, 63 illustrations in colour
Topics