Biomechanics: Trends in Modeling and Simulation
Editors: Holzapfel, Gerhard A., Ogden, Ray W. (Eds.)
Free Preview- Presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues
- Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues
- The essential ingredients of continuum mechanics are provided
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- About this book
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The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues.
The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
- Table of contents (7 chapters)
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Mixture Theory for Modeling Biological Tissues: Illustrations from Articular Cartilage
Pages 1-51
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A Bio-chemo-mechanical Model for Cell Contractility, Adhesion, Signaling, and Stress-Fiber Remodeling
Pages 53-81
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Nonlinear Continuum Mechanics and Modeling the Elasticity of Soft Biological Tissues with a Focus on Artery Walls
Pages 83-156
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Microstructure and Mechanics of Human Aortas in Health and Disease
Pages 157-192
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Arterial and Atherosclerotic Plaque Biomechanics with Application to Stent Angioplasty Modeling
Pages 193-231
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Table of contents (7 chapters)
- Download Preface 1 PDF (51.3 KB)
- Download Sample pages 2 PDF (1.4 MB)
- Download Table of contents PDF (46.5 KB)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Biomechanics: Trends in Modeling and Simulation
- Editors
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- Gerhard A. Holzapfel
- Ray W. Ogden
- Series Title
- Studies in Mechanobiology, Tissue Engineering and Biomaterials
- Series Volume
- 20
- Copyright
- 2017
- Publisher
- Springer International Publishing
- Copyright Holder
- Springer International Publishing Switzerland
- eBook ISBN
- 978-3-319-41475-1
- DOI
- 10.1007/978-3-319-41475-1
- Hardcover ISBN
- 978-3-319-41473-7
- Softcover ISBN
- 978-3-319-82364-5
- Series ISSN
- 1868-2006
- Edition Number
- 1
- Number of Pages
- IX, 316
- Number of Illustrations
- 66 b/w illustrations, 63 illustrations in colour
- Topics
