Overview
Compiles the latest research on the study of epigenetics and proteomics of leukemia
Introduces computational methods to evaluate and analyze changes in proteome and chromatin remodeling
Demonstrates synergy of biological methods with computational informatics for leukemia research
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Table of contents (9 chapters)
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Front Matter
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Proteomics in Leukemia
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Front Matter
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Protein Localization in Leukemia
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Front Matter
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Back Matter
Keywords
About this book
This book reviews the current state of epigenetics and proteomics of leukemia and introduces the methods that are important to process and evaluate these factors in leukemia. In particular, epigenetic modifiers and their inhibitors in leukemia treatment as well as approaches to the epigenetic treatment of leukemia are covered. Various computational methods for proteome analysis are also described in detail, including 2DE fractionation and visualization, proteomic data processing, image acquisition and data anlaysis, and more. Protein localization in leukemia is also covered, in addition to the future of leukemia therapy.
Epigenetics and Proteomics of Leukemia is an ideal book for advanced biomedical scientists and students, medical doctors and students, bioinformatics and health informatics researchers, computational biologists, structural biologists, systems biologists, and bioengineers.
Authors and Affiliations
About the authors
Department of Molecular Cell Biology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania
Dalius NAVAKAUSKAS, Dr. Prof.
Department of Electronic Systems, Faculty of Electronics, Vilnius Gediminas Technical University, Naugarduko st. 41-426, LT-03227 Vilnius, Lithuania
Veronika BORUTINSKAITĖ, Dr.
Department of Molecular Cell Biology, Institute of Biochemistry, Life Sciences Center, Vilnius University, Sauletekio av. 7, LT-10257 Vilnius, Lithuania
Dalius MATUZEVIČIUS, Dr. Assoc. Prof.
Department of Electronic Systems, Faculty of Electronics, Vilnius Gediminas Technical University, Naugarduko st. 41-413, LT-03227 Vilnius, Lithuania
Bibliographic Information
Book Title: Epigenetics and Proteomics of Leukemia
Book Subtitle: A Synergy of Experimental Biology and Computational Informatics
Authors: R¯uta Navakauskien˙e, Dalius Navakauskas, Veronika Borutinskait˙e, Dalius Matuzevi˘cius
DOI: https://doi.org/10.1007/978-3-030-68708-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-68707-6Published: 15 September 2021
Softcover ISBN: 978-3-030-68710-6Published: 16 September 2022
eBook ISBN: 978-3-030-68708-3Published: 14 September 2021
Edition Number: 1
Number of Pages: LIX, 406
Number of Illustrations: 49 b/w illustrations, 107 illustrations in colour
Topics: Proteomics, Cancer Research, Biomedical Engineering/Biotechnology, Genetics and Genomics, Computational Biology/Bioinformatics, Biomedical Engineering and Bioengineering