X-Ray Phase-Contrast Tomography
Underlying Physics and Developments for Breast Imaging
Authors: Brombal, Luca
Free Preview- Nominated as an outstanding PhD thesis by the Italian National Institute of Nuclear Physics and the University of Trieste
- Makes important contribution to the optimization of x-ray tomography using synchrotron radiation
- Adds to the weight of evidence supporting the transition of phase contrast imaging from synchrotrons to hospitals
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- About this book
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X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
- Table of contents (8 chapters)
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Introduction
Pages 1-3
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Physics of Propagation-Based X-Ray Tomography
Pages 5-22
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Propagation-Based Breast CT and SYRMA-3D Project
Pages 23-34
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Detector and Pre-processing
Pages 35-54
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Experimental Optimization of Propagation-Based BCT
Pages 55-84
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Table of contents (8 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- X-Ray Phase-Contrast Tomography
- Book Subtitle
- Underlying Physics and Developments for Breast Imaging
- Authors
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- Luca Brombal
- Series Title
- Springer Theses
- Copyright
- 2020
- Publisher
- Springer International Publishing
- Copyright Holder
- The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG
- eBook ISBN
- 978-3-030-60433-2
- DOI
- 10.1007/978-3-030-60433-2
- Hardcover ISBN
- 978-3-030-60432-5
- Series ISSN
- 2190-5053
- Edition Number
- 1
- Number of Pages
- XIII, 140
- Number of Illustrations
- 15 b/w illustrations, 53 illustrations in colour
- Topics
