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Clinical Neuroimmunology

Multiple Sclerosis and Related Disorders

  • Simplified understanding of immunology, immunotherapy and immune-mediated disorders of the nervous system
  • Updated and expanded new edition covering the latest treatments and emerging concepts, such as Microbiome
  • Authored by experts in the field for clinicians that treat patients with neurologic disorders and other systemic autoimmune diseases

Part of the book series: Current Clinical Neurology (CCNEU)

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Softcover Book USD 99.99
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Hardcover Book USD 139.99
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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xiii
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. Introduction to Neuroimmunology

      • Patricia K. Coyle
      Pages 3-15
    3. Principles of Immunotherapy

      • Jennifer Joscelyn, Javier Ochoa-Repáraz, Lloyd Kasper
      Pages 17-42
  3. Multiple Sclerosis

    1. Front Matter

      Pages 43-43
    2. Immunopathogenesis

      • Patricia K. Coyle
      Pages 45-69
    3. Epidemiology and Genetics

      • Tina Roostaei, Philip L. De Jager
      Pages 71-87
    4. Clinical Features, Symptom Management, and Diagnosis

      • Jacqueline F. Rosenthal, James M. Stankiewicz, Guy J. Buckle
      Pages 89-108
    5. Magnetic Resonance Imaging and Analysis in Multiple Sclerosis

      • Dejan Jakimovski, Deepa P. Ramasamy, Robert Zivadinov
      Pages 109-136
    6. Disease-Modifying Agents

      • Syed A. Rizvi
      Pages 137-157
    7. Clinical Decision-Making in the Management of Multiple Sclerosis

      • Syed A. Rizvi, Joshua A. Stone, Saima T. Chaudhry, Nichola Haddad, Brian Wong, Jennifer O. Grimes
      Pages 159-177
    8. Multiple Sclerosis in Children

      • Charles D. Tyshkov, Leigh Elkins Charvet, Lauren B. Krupp
      Pages 179-196
    9. Vitamin D and Multiple Sclerosis

      • Michael J. Bradshaw, Michael F. Holick, James M. Stankiewicz
      Pages 197-212
  4. Other CNS inflammatory Disorders

    1. Front Matter

      Pages 213-213
    2. Acute Disseminated Encephalomyelitis

      • Patricia K. Coyle
      Pages 215-226
    3. Neuromyelitis Optica Spectrum Disorders

      • Jonathan F. Cahill
      Pages 227-234
    4. Paraneoplastic and Other Autoimmune Disorders

      • Alexander Mohler, Mayra Montalvo, Julie Roth
      Pages 235-255
  5. Peripheral Nervous System Disorders

    1. Front Matter

      Pages 283-283
    2. Immunologic Disorders of Neuromuscular Junction and Muscle

      • James M. Gilchrist, John E. Donahue
      Pages 285-298

About this book

This comprehensive, up-to-date book is designed to make recent developments in neuroimmunology accessible to medical professionals in the field. The field of neuroimmunology is complex and rapidly evolving, especially with the current improvements in targeted biologic therapies. This resource concisely offers clear explanations of these scientific and clinical advancements.

Divided into five parts, the book begins with an in-depth introduction to neuroimmunology and the principles of immunotherapy. Section two consists of eight chapters devoted to multiple sclerosis, including discussions on the clinical features of the disease as well as symptom management and diagnosis. Subsequent chapters then dive into other central nervous system inflammatory disorders such as neuromyelitis optica, autoimmune encephalopathies, and immunological aspects of cancer. Following this are two chapters that examine distinct aspects of autoimmune disorders of the peripheral nervous system.Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various systemic rheumatic diseases.

Following its successful predecessor edition, Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders, Second Edition is positioned to be an invaluable asset to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.



Editors and Affiliations

  • Rhode Island Hospital and Alpert Medical School of Brown University, Brown Neurology, Providence, USA

    Syed A. Rizvi, Jonathan F. Cahill

  • Department of Neurology, MS Comprehensive Care Center, Stony Brook University Medical Center, Stony Brook, USA

    Patricia K. Coyle

About the editors

Syed A. Rizvi, MD, EMHL
Associate Professor
Rhode Island Hospital
Department of Clinical Neurosciences
Providence, RI 02903


Jonathan F. Cahill, MD
Assistant Professor of Neurology
Rhode Island Hospital and Alpert Medical School of Brown University
Department of Neurology
Providence, RI 02903


Patricia K. Coyle, MD
Professor and Vice Chair 
Director, MS Comprehensive Care Center 
Stony Brook University Medical Center 
Department of Neurology
Stony Brook, NY 11794



Bibliographic Information

  • Book Title: Clinical Neuroimmunology

  • Book Subtitle: Multiple Sclerosis and Related Disorders

  • Editors: Syed A. Rizvi, Jonathan F. Cahill, Patricia K. Coyle

  • Series Title: Current Clinical Neurology

  • DOI: https://doi.org/10.1007/978-3-030-24436-1

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-24435-4Published: 11 November 2019

  • Softcover ISBN: 978-3-030-24438-5Published: 11 November 2020

  • eBook ISBN: 978-3-030-24436-1Published: 24 October 2019

  • Series ISSN: 1559-0585

  • Series E-ISSN: 2524-4043

  • Edition Number: 2

  • Number of Pages: XIII, 353

  • Number of Illustrations: 24 b/w illustrations, 22 illustrations in colour

  • Topics: Neurology, Internal Medicine, General Practice / Family Medicine

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access