Calcium Signaling

1. Front Matter

   Pages i-xiii

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2. Calcium Signaling: From Basic to Bedside

   • Md. Shahidul Islam

   Pages 1-6

3. Measuring Ca2+ in Living Cells

   • Joseph Bruton, Arthur J. Cheng, Håkan Westerblad

   Pages 7-26

4. High-Throughput Fluorescence Assays for Ion Channels and GPCRs

   • Irina Vetter, David Carter, John Bassett, Jennifer R. Deuis, Bryan Tay, Sina Jami et al.

   Pages 27-72

5. Imaging Native Calcium Currents in Brain Slices

   • Karima Ait Ouares, Nadia Jaafari, Nicola Kuczewski, Marco Canepari

   Pages 73-91

6. Molecular Diversity of Plasma Membrane Ca2+ Transporting ATPases: Their Function Under Normal and Pathological Conditions

   • Luca Hegedűs, Boglárka Zámbó, Katalin Pászty, Rita Padányi, Karolina Varga, John T. Penniston et al.

   Pages 93-129

7. A Role for SERCA Pumps in the Neurobiology of Neuropsychiatric and Neurodegenerative Disorders

   • Aikaterini Britzolaki, Joseph Saurine, Benjamin Klocke, Pothitos M. Pitychoutis

   Pages 131-161

8. Cytoplasmic Calcium Buffering: An Integrative Crosstalk

   • Juan A. Gilabert

   Pages 163-182

9. An Update to Calcium Binding Proteins

   • Jacobo Elíes, Matilde Yáñez, Thiago M. C. Pereira, José Gil-Longo, David A. MacDougall, Manuel Campos-Toimil

   Pages 183-213

10. Phospholipase C

    • Colin A. Bill, Charlotte M. Vines

    Pages 215-242

11. New Insights in the IP3 Receptor and Its Regulation

    • Jan B. Parys, Tim Vervliet

    Pages 243-270

12. Expression of the Inositol 1,4,5-Trisphosphate Receptor and the Ryanodine Receptor Ca2+-Release Channels in the Beta-Cells and Alpha-Cells of the Human Islets of Langerhans

    • Fabian Nordenskjöld, Björn Andersson, Md. Shahidul Islam

    Pages 271-279

13. Evolution of Excitation-Contraction Coupling

    • John James Mackrill, Holly Alice Shiels

    Pages 281-320

14. Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels

    • Naohiro Yamaguchi

    Pages 321-336

15. Sarco-Endoplasmic Reticulum Calcium Release Model Based on Changes in the Luminal Calcium Content

    • Agustín Guerrero-Hernández, Víctor Hugo Sánchez-Vázquez, Ericka Martínez-Martínez, Lizeth Sandoval-Vázquez, Norma C. Perez-Rosas, Rodrigo Lopez-Farias et al.

    Pages 337-370

16. Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores

    • Antony Galione, Kai-Ting Chuang

    Pages 371-394

17. Calcium Signaling in the Heart

    • Derek A. Terrar

    Pages 395-443

18. Molecular Basis and Regulation of Store-Operated Calcium Entry

    • Jose J. Lopez, Isaac Jardin, Letizia Albarrán, Jose Sanchez-Collado, Carlos Cantonero, Gines M. Salido et al.

    Pages 445-469

19. Canonical Transient Potential Receptor-3 Channels in Normal and Diseased Airway Smooth Muscle Cells

    • Yong-Xiao Wang, Lan Wang, Yun-Min Zheng

    Pages 471-487

20. Pathophysiological Significance of Store-Operated Calcium Entry in Cardiovascular and Skeletal Muscle Disorders and Angiogenesis

    • Javier Avila-Medina, Isabel Mayoral-González, Isabel Galeano-Otero, Pedro C. Redondo, Juan A. Rosado, Tarik Smani

    Pages 489-504

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative.

The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

• Calcium signaling
• Cell biology
• Cell signaling
• Ion channels
• Signal transduction
• Receptors

• Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

  Md. Shahidul Islam

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