- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Buy this book
- About this book
-
This volume details a valuable collection of protocols and reviews, such as emerging experimental and theoretical approaches. These approaches have resulted in a substantial improvement in the understanding of chromosome architecture. Chromosome Architecture: Methods and Protocols guides readers through cutting-edge interdisciplinary methods which allow for an understanding of architecture of chromosomes with exceptionally enhanced resolution, both in terms of space and time. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Chromosome Architecture: Methods and Protocols aims to ensure successful results in the further study of this vital field.
- Table of contents (19 chapters)
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New Advances in Chromosome Architecture
Pages 1-3
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Single-Molecule Narrow-Field Microscopy of Protein–DNA Binding Dynamics in Glucose Signal Transduction of Live Yeast Cells
Pages 5-15
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Single-Molecule Imaging to Characterize the Transport Mechanism of the Nuclear Pore Complex
Pages 17-35
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Using Fluorescence Recovery After Photobleaching (FRAP) to Study Dynamics of the Structural Maintenance of Chromosome (SMC) Complex In Vivo
Pages 37-46
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Imaging DNA Structure by Atomic Force Microscopy
Pages 47-60
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Table of contents (19 chapters)
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Bibliographic Information
- Bibliographic Information
-
- Book Title
- Chromosome Architecture
- Book Subtitle
- Methods and Protocols
- Editors
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- Mark C. Leake
- Series Title
- Methods in Molecular Biology
- Series Volume
- 1431
- Copyright
- 2016
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4939-3631-1
- DOI
- 10.1007/978-1-4939-3631-1
- Hardcover ISBN
- 978-1-4939-3629-8
- Softcover ISBN
- 978-1-4939-8100-7
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- X, 290
- Number of Illustrations
- 12 b/w illustrations, 65 illustrations in colour
- Topics