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Methods in Pharmacology and Toxicology

Immuno-Oncology

Cellular and Translational Approaches

Editors: Tan, Seng-Lai (Ed.)

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  • Features practical approaches to immunotherapeutic cancer research
  • Contains key implementation advice from the experts
  • Provides guidance for developing next generation translational assays
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eBook £111.50
price for United Kingdom (gross)
  • ISBN 978-1-07-160171-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £139.99
price for United Kingdom (gross)
  • ISBN 978-1-07-160170-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book serves as a guide for identifying and applying commonly used cell-based translational assays as well as for assessing the therapeutic potential of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters within will provide readers with a baseline understanding of the pros and cons as well as key considerations for applying assays that are more reflective of the human immune-tumor microenvironment in order to increase their translatability into the clinic. Written for the Methods in Pharmacology and Toxicology series, the contents of this volume include the kind of specifics and real-world implementation advice to ensure success in the lab. 
Authoritative and practical, Immuno-Oncology: Cellular and Translational Approaches aims to aid researchers working on biotechnology and pharmaceutical efforts to search for the next generation of safer and more effective cancer immunotherapeutics.

Table of contents (13 chapters)

Table of contents (13 chapters)
  • An In Vitro System Combining Tumor Cells and Lymphocytes to Predict the In Vivo Response of Immunomodulatory Antibodies

    Pages 1-12

    Dai, Min (et al.)

  • High-Throughput Direct Cell Counting Method for Immuno-Oncology Functional Assays Using Image Cytometry

    Pages 13-34

    Chan, Leo Li-Ying

  • In Vitro Functional Assay Using Real-Time Cell Analysis for Assessing Cancer Immunotherapeutic Agents

    Pages 35-50

    Xi, Biao (et al.)

  • Assessing the Potency of T Cell-Redirecting Therapeutics Using In Vitro Cancer Cell Killing Assays

    Pages 51-72

    Dobrzycki, Tomasz (et al.)

  • Induction and Potential Reversal of a T Cell Exhaustion-Like State: In Vitro Potency Assay for Functional Screening of Immune Checkpoint Drug Candidates

    Pages 73-88

    Kleiman, Eden (et al.)

Buy this book

eBook £111.50
price for United Kingdom (gross)
  • ISBN 978-1-07-160171-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover £139.99
price for United Kingdom (gross)
  • ISBN 978-1-07-160170-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Immuno-Oncology
Book Subtitle
Cellular and Translational Approaches
Editors
  • Seng-Lai Tan
Series Title
Methods in Pharmacology and Toxicology
Copyright
2020
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-07-160171-6
DOI
10.1007/978-1-0716-0171-6
Hardcover ISBN
978-1-07-160170-9
Series ISSN
1557-2153
Edition Number
1
Number of Pages
X, 262
Number of Illustrations
8 b/w illustrations, 83 illustrations in colour
Topics