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Drug Discovery and Drug Development

The Indian Narrative

Editors:

  • Discusses the successes and critically assesses the failures of new drug discovery efforts
  • Shares insights and updates on drug development in a wide range of areas such as metabolic diseases, parasitic diseases, cancer, and microbial diseases
  • Offers an inside view of the history of drug discovery in the Indian pharmaceutical industry

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii
  2. Traditional Medical System (TMS) for Sustainable Healthcare in India

    • Pulok K. Mukherjee, Subhadip Banerjee, Chandra Kant Katiyar, Shivani Sharma, Naibedya Chattopadhyay
    Pages 1-36
  3. Modern Drug Discovery and Development for TB: The India Narrative

    • Tanjore S. Balganesh, Jagadeesh J. Bhat, Bheemarao Ugarkar
    Pages 37-61
  4. Indian Discovery Effort in the Quest of Novel Antibiotics

    • Mahesh V. Patel, Sachin S. Bhagwat, Prasad K. Deshpande
    Pages 63-95
  5. Modern Drug Discovery and Development in the Area of Leishmaniasis

    • Neena Goyal, Manveer Patel, Sanjay Batra
    Pages 123-158
  6. Introduction to Diabetes and Prevalence in India

    • Parimal Misra, Ranjan Chakrabarti
    Pages 159-163
  7. Type 2 Diabetes Mellitus: Marketed Drugs and Mechanisms

    • Parimal Misra, Ranjan Chakrabarti
    Pages 165-177
  8. Modern Drug Discovery and Development in the Area of Cancer: Indian Context

    • Tapas K. Kundu, Anand P. Kulkarni, Dipak Datta, Sweta Sikder
    Pages 227-253
  9. Regulatory Requirements and Quality Standards in India’s Clinical Trials Journey

    • Bobby George, Shrinivas Krishnarao Kulkarni, Nilima A. Kshirsagar
    Pages 283-302
  10. New Drug Discovery and Development: Indian Pharmaceutical Industry

    • Nagarajan Kuppuswamy, Srinivas Nanduri, Venkateswarlu Akella
    Pages 303-376

About this book

Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India’s New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR.  

Editors and Affiliations

  • NCR Biotech Science Cluster, Translational Health Science and Technology Institute, Faridabad, India

    Madhu Dikshit

About the editor

Dr Madhu Dikshit, a highly respected researcher and former Director of the CSIR-Central Drug Research Institute, Lucknow, India, has made significant contributions to the general area of Molecular Pharmacology with a special interest in redox biology. Dr Dikshit’s research has impacted the area of neutrophil biology by enhancing our understanding of e.g. chemotaxis, phagocytosis, apoptosis and also differentiation. Her pioneering work has helped identify the molecular mechanisms involved in the translocation of Nitric Oxide Synthase to the phagosomal compartment and the inflammatory potential of neutrophil extracellular traps. At the CSIR-CDRI, she initiated and led the successful anti-thrombotic drug discovery program, in the context of which two new chemical entities advanced to the pre-clinical stage and one has recently received approval for Phase I clinical trials. Dr Dikshit has published more than 170 papers in peer-reviewed journals, holds eight patents and has supervised more than 30 PhD students. Presently she is the National Chair at Translational Health Sciences & Technology Institute (THSTI), Faridabad and heads its Non-Communicable Disease Program.

Bibliographic Information

  • Book Title: Drug Discovery and Drug Development

  • Book Subtitle: The Indian Narrative

  • Editors: Madhu Dikshit

  • DOI: https://doi.org/10.1007/978-981-15-8002-4

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2021

  • Hardcover ISBN: 978-981-15-8001-7Published: 11 February 2021

  • Softcover ISBN: 978-981-15-8004-8Published: 11 February 2022

  • eBook ISBN: 978-981-15-8002-4Published: 10 February 2021

  • Edition Number: 1

  • Number of Pages: XIII, 376

  • Number of Illustrations: 147 b/w illustrations, 44 illustrations in colour

  • Topics: Pharmacology/Toxicology, Biotechnology, Biomedicine, general

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access