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Diagnostic Meta-Analysis

A Useful Tool for Clinical Decision-Making

  • Book
  • © 2018

Overview

Editors:
  1. Giuseppe Biondi-Zoccai

    1. Department of Medico-Surgical Sciences, Sapienza University of Rome, Latina, Italy

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  • First-ever comprehensive book devoted to this topic
  • Hands-on approach and essential guidance on how to interpret and independently conduct a meta-analysis of diagnostic test accuracy studies
  • Multinational contributor team, presenting a multidisciplinary and multidimensional approach to umbrella reviews

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Part I

    1. Front Matter

      Pages 1-1
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    2. Introduction to Clinical Diagnosis

      • Giuseppe Biondi-Zoccai, Mariangela Peruzzi, Simona Mastrangeli, Giacomo Frati
      Pages 3-9

    3. The Evidence Hierarchy

      • Mical Paul
      Pages 11-17

    4. Peculiarities of Diagnostic Test Accuracy Studies

      • Giuseppe Biondi-Zoccai, Simona Mastrangeli, Mariangela Peruzzi, Giacomo Frati
      Pages 19-30

    5. Meta-Analyses of Clinical Trials Versus Diagnostic Test Accuracy Studies

      • Michail Tsagris, Konstantinos C. Fragkos
      Pages 31-40

  3. Part II

    1. Front Matter

      Pages 41-41
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    2. Designing the Review

      • José Mauro Madi, Machline Paim Paganella, Isnard Elman Litvin, Eliana Marcia Wendland
      Pages 43-58

    3. Registering the Review

      • Alison Booth, Julie Jones-Diette
      Pages 59-75

    4. Searching for Diagnostic Test Accuracy Studies

      • Su Golder, Julie Glanville
      Pages 77-91

    5. Abstracting Evidence

      • Luca Testa, Mario Bollati
      Pages 93-98

    6. Appraising Evidence

      • Valentina Pecoraro
      Pages 99-114

    7. Synthesizing Evidence

      • Paul-Christian Bürkner
      Pages 115-124

    8. Appraising Heterogeneity

      • Antonia Zapf
      Pages 125-160

    9. Statistical Packages for Diagnostic Meta-Analysis and Their Application

      • Philipp Doebler, Paul-Christian Bürkner, Gerta Rücker
      Pages 161-181

    10. Network Meta-Analysis of Diagnostic Test Accuracy Studies

      • Gerta Rücker
      Pages 183-197

    11. Transition to Intervention Meta-Analysis

      • Umberto Benedetto, Colin Ng
      Pages 199-203

    12. Updating Diagnostic Test Accuracy Systematic Reviews: Which, When, and How Should They Be Updated?

      • Ersilia Lucenteforte, Alessandra Bettiol, Salvatore De Masi, Gianni Virgili
      Pages 205-227

  4. Part III

    1. Front Matter

      Pages 229-229
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    2. Diagnostic Meta-Analysis: Case Study in Endocrinology

      • Kosma Wolinski
      Pages 231-247
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Keywords

About this book

This book is the first exclusively devoted to the systematic synthesis of diagnostic test accuracy studies. It builds upon the major recent developments in reporting standards, search methods, and, in particular, statistical tools specifically devoted to diagnostic studies. In addition, it borrows extensively from the latest advances in systematic reviews and meta-analyses of intervention studies. After a section dedicated to methods for designing reviews, synthesizing evidence and appraising inconsistency in research, the application of these approaches is demonstrated in the context of case studies from various clinical disciplines.

Diagnosis is central in medical decision-making, and in many other fields of human endeavor, such as education and psychology. The plurality of sources of evidence on diagnostic test accuracy poses a huge challenge for practitioners and researchers, as do the multiple dimensions of evidence validity, which include sensitivity, specificity, predictive values, and likelihood ratios.

This book offers an invaluable resource for anyone aiming to improve decision-making processes in diagnosis, classification or risk prognostication, from epidemiologists to biostatisticians, radiologists, laboratory physicians and graduate students, as any physician interested in refining his methodological skills in clinical diagnosis.

Reviews

“In this book, the authors present pragmatic and useful summaries of the necessary steps for conducting diagnostic accuracy meta-analysis. … This is a great addition to this field, which has lacked a comprehensive introductory book intended for beginners. While the Cochrane handbook also provides a good summary of this topic, this book reaches a broader audience.” (Michihiko Goto, Doody's Book Reviews, April 12, 2019)

Editors and Affiliations

  • Department of Medico-Surgical Sciences, Sapienza University of Rome, Latina, Italy

    Giuseppe Biondi-Zoccai

About the editor

Giuseppe Biondi-Zoccai is Associate Professor in Cardiology in the Department of Medico-Surgical Sciences and Biotechnologies of Sapienza University of Rome. He has got an established expertise in evidence-based cardiovascular medicine and is the founder of the Meta-analysis and Evidence-based medicine Training in Cardiology (METCARDIO) Collaboration. He has published more than 600 articles indexed in MEDLINE, including more than 200 systematic reviews, meta-analyses, or umbrella reviews, and he is the editor of the first books devoted to network meta-analyses and umbrella reviews. 

Bibliographic Information

  • Book Title: Diagnostic Meta-Analysis

  • Book Subtitle: A Useful Tool for Clinical Decision-Making

  • Editors: Giuseppe Biondi-Zoccai

  • DOI: https://doi.org/10.1007/978-3-319-78966-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-78965-1Published: 16 August 2018

  • Softcover ISBN: 978-3-030-07691-7Published: 19 January 2019

  • eBook ISBN: 978-3-319-78966-8Published: 24 July 2018

  • Edition Number: 1

  • Number of Pages: XVII, 319

  • Number of Illustrations: 30 b/w illustrations, 15 illustrations in colour

  • Topics: Epidemiology, Biostatistics, Statistics for Life Sciences, Medicine, Health Sciences, Clinical Psychology, Laboratory Medicine

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