Overview
One-stop solution for the fundamental principles and treatment options of ocular pharmacology and pharmacy, from historic origin to future perspectives
Rationalizes ocular therapeutics using pharmacological principles and with a scope for developing newer agents
Covers key aspects of diverse agents used in day-to-day ophthalmology practice, from diagnostics to therapeutics
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Table of contents (20 chapters)
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Front Matter
Keywords
- Autonomic Drugs for the Eye
- Blood Ocular Barriers
- Extemporaneous Formulations for the Eye
- Eye Medications
- Glaucoma Therapy
- History of Eye Drugs
- Innovative Ocular Drug Delivery
- Novel Targets in Eye Research
- Ocular Biochemistry
- Ocular Drug Research
- Ocular Pharmacogenomics
- Ocular Pharmacokinetics
- Ocular Pharmacy
- Ocular Stem Cell Therapy
- Ocular Toxicity
- Ocular Use of Mucoadhesive Polymer
- Photodynamic Therapy
- Side Effects of Eye Drugs
About this book
This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents.
Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use.
Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.
Reviews
“The intent is to provide a stimulus for research scholars and practitioners to think about expanding their domain understanding and to broaden their exploratory thoughts. This comprehensive resource on ocular pharmacology achieves this goal. This book will be of value for practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, and research scholars. … This is a well-written, complete resource on all aspects of drugs used in the diagnosis and treatment of ocular disease.” (Thomas L. Pazdernik, Doody's Book Reviews, June, 2016)
Editors and Affiliations
About the editor
Thirumurthy Velpandian is a Professor, heading the Ocular Pharmacology & Pharmacy Division at Dr. R.P. Centre for Ophthalmic Sciences at All India Institute of Medical Sciences, New Delhi. He has been involved in research, teaching and pharmaceutical patient care activities of ophthalmology. His area of interest is ocular pharmacokinetics of drugs, with reference to xenobiotic transporters across blood-ocular barriers, and developing animal models for various ophthalmic conditions. Pre-clinical drug development and delivery approaches are ongoing research collaborations. His laboratory is also involved in tear lipidomics, ocular QSPR, pharmacogenomics, as well as chemical and environmental issues related to ocular toxicity. He has been a visiting Professor to Harvard-MIT and a recipient of the Dr. Vinod Kumar Bhargava Award (2014) for Clinical Pharmacology and Drug Discovery by the National Academy of Medical Sciences, India. He currently serves as an Editor (Pharmacology) of Indian J Physiology and Pharmacology.
Bibliographic Information
Book Title: Pharmacology of Ocular Therapeutics
Editors: Thirumurthy Velpandian
DOI: https://doi.org/10.1007/978-3-319-25498-2
Publisher: Adis Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-25496-8Published: 10 March 2016
Softcover ISBN: 978-3-319-79802-8Published: 24 April 2018
eBook ISBN: 978-3-319-25498-2Published: 29 February 2016
Edition Number: 1
Number of Pages: XIV, 535
Number of Illustrations: 40 b/w illustrations, 67 illustrations in colour
Topics: Pharmacology/Toxicology, Ophthalmology