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Cancer Immunology

Bench to Bedside Immunotherapy of Cancers

  • Describes in detail novel strategies in cancer immunotherapy and targeting of tumor immunosuppression

  • Provides a bench to bedside approach to the immunology of cancers, with a focus on clinical aspects

  • Updated and revised edition featuring additional chapters on topics of emerging importance

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xl
  2. Frontiers in Cancer Immunotherapy

    • Joseph F. Murphy
    Pages 1-23
  3. Novel Strategy of Cancer Immunotherapy: Spiraling Up

    • Irina Zh. Shubina, Irina O. Chikileva, Igor V. Samoylenko, Mikhail V. Kiselevskiy
    Pages 25-39
  4. Personalized Prevention Strategies to Defeat Cancer

    • Anna Maria Berghella, Anna Aureli, Angelica Canossi, Giuseppe Marulli, Roberto Lattanzio, Giancarlo Di Gregorio et al.
    Pages 41-51
  5. Tumor Antigen Identification for Cancer Immunotherapy

    • Maryam Balibegloo, Mahsa Keshavarz-Fathi, Nima Rezaei
    Pages 53-59
  6. Strategies to Target Tumor Immunosuppression

    • Georgia Koutsoumpli, Oana Draghiciu, Hans W Nijman, Cesar Oyarce, Toos Daemen
    Pages 61-83
  7. Overcoming Cancer Tolerance with Immune Checkpoint Blockade

    • John W. Myers, George E. Peoples, Guy T. Clifton
    Pages 85-128
  8. Gene Therapy and Genetic Vaccines

    • Sara Hemmati, Mahsa Keshavarz-Fathi, Sepideh Razi, Nima Rezaei
    Pages 129-142
  9. Hematopoietic Stem Cell Transplantation and Lymphodepletion for the Treatment of Cancer

    • Kristen M. Barr, Amin Pastaki Khoshbin, Jill A. Gershan, Bryon D. Johnson
    Pages 143-156
  10. Combination of Chemotherapy and Cytokine Therapy in Treatment of Cancers

    • M. Malvicini, Guillermo D. Mazzolini
    Pages 169-182
  11. Type I Interferons: History and Perspectives as Immunotherapeutic Agents Against Cancer

    • Carolina Mendonça Gorgulho, Graziela Gorete Romagnoli, Ramon Kaneno
    Pages 183-197
  12. T-Cell Immunotherapy: From Synthetic Biology to Clinical Practice

    • Dina Schneider, Rimas J. Orentas
    Pages 199-218
  13. Role of γδ T Lymphocytes in Cancer Immunosurveillance and Immunotherapy

    • Telma Lança, Daniel V. Correia, Bruno Silva-Santos
    Pages 219-250
  14. Adoptive T-Cell Therapy: Optimizing Chemokine Receptor-Mediated Homing of T-Cells in Cancer Immunotherapy

    • Imran Siddiqui, Debora Vignali, Marinos Kallikourdis, Alberto Mantovani, Paola Allavena
    Pages 251-271
  15. Monoclonal Antibodies for Cancer Immunotherapy

    • Amir-Hassan Zarnani, Davood Jafari, Mahmood Bozorgmehr, Mahdi Shabani, Leila Barzegar-Yarmohammadi, Fatemeh Ghaemimanesh et al.
    Pages 273-312
  16. Toll-Like Receptor Pathway and Its Targeting in Treatment of Cancers

    • Seyed Hossein Aalaei-Andabili, Neda Amini, Farnaz Delavari, Mahsa Keshavarz-Fathi, Shaherin Basith, Sangdun Choi et al.
    Pages 313-325
  17. Recent Advances in the Use of NK Cells Against Cancer

    • Amy E. Gillgrass, Tamara Krneta, Sophie M. Poznanski, Ali A. Ashkar
    Pages 327-348
  18. Dendritic Cell Vaccines for Cancer Therapy: Fundamentals and Clinical Trials

    • Graziela Gorete Romagnoli, Ramon Kaneno
    Pages 349-364
  19. Tumor-Associated Macrophages and Cancer Development

    • Ken-ichi Isobe, Hengyi Xiao
    Pages 365-372

About this book

This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are included on, for example, cancer immunoprevention, aptamer-mediated cancer gene therapy, haploidentical bone marrow transplantation for pediatric malignancies, and nanoimmunotherapy.

The book is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Other volumes in the series address the translational medicine context and cancer immunotherapy for organ-specific tumors. Cancer Immunology: Bench to Bedside Immunotherapy of Cancers will be of special value to clinical immunologists, hematologists, and oncologists.

 

Editors and Affiliations

  • Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

    Nima Rezaei

About the editor

Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also undertook a short-term fellowship of Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology, School of Medicine, Tehran University of Medical Sciences. He is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences; Director of the Global Academic Program, Tehran University of Medical Sciences; and co-founder and Deputy President of the Research Center for Immunodeficiencies. He is also the Founding President of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the director of more than 50 research projects and has designed and participated in several international collaborative projects. He is an editorial assistant or board member for more than 30 international journals. He has edited more than 20 books, has presented more than 450 lectures/posters in congresses/meetings, and has published more than 750 articles in international scientific journals

 

Bibliographic Information

  • Book Title: Cancer Immunology

  • Book Subtitle: Bench to Bedside Immunotherapy of Cancers

  • Editors: Nima Rezaei

  • DOI: https://doi.org/10.1007/978-3-030-50287-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-50286-7Published: 25 September 2020

  • Softcover ISBN: 978-3-030-50289-8Published: 27 September 2021

  • eBook ISBN: 978-3-030-50287-4Published: 24 September 2020

  • Edition Number: 2

  • Number of Pages: XL, 658

  • Number of Illustrations: 7 b/w illustrations, 46 illustrations in colour

  • Topics: Oncology, Immunology, Internal Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access