Plasma Cancer Therapy

1. Front Matter

   Pages i-x

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2. Introduction: Plasma for Cancer Therapy

   • Michael Keidar

   Pages 1-13

3. Cold Atmospheric Pressure Plasma Sources for Cancer Applications

   • Mounir Laroussi, Lan Lan Nie, XinPei Lu

   Pages 15-51

4. Cold Atmospheric Plasma Sources for Cancer Applications and Their Diagnostics

   • Eun Ha Choi

   Pages 53-73

5. Cancer Applications Overview

   • Michael Keidar, Alexander Fridman

   Pages 75-89

6. Biochemistry of Plasma in Cancer Therapy

   • Georg Bauer, Sander Bekeschus

   Pages 91-142

7. Plasma-Activated Solution in Cancer Treatment

   • Hiromasa Tanaka, Mounir Laroussi, Sander Bekeschus, Dayun Yan, Masaru Hori, Michael Keidar

   Pages 143-168

8. Plasma and Plasma–Cell Interaction Simulations

   • Annemie Bogaerts, Jonas Van der Paal, Pepijn Heirman, Jamoliddin Razzokov, Maksudbek Yusupov

   Pages 169-208

9. Immunology in Plasma Cancer Treatment

   • Sander Bekeschus, Georg Bauer, Vandana Miller

   Pages 209-222

10. Adaptive Plasma and Machine Learning

    • Taeyoung Lee, Michael Keidar

    Pages 223-250

11. Fundamental Studies of the Effect of Plasma on Plasmid DNA, Cancer Cells, and Virus

    • Xu Yan, XinPei Lu

    Pages 251-270

12. Current Understanding of Mechanisms in Plasma Cancer Therapy and Recent Advances in Technology

    • Dayun Yan, Li Lin, Eda Gjika, Carles Corbella, Alisa Malyavko, Isak I. Beilis et al.

    Pages 271-287

13. Clinical Applications of Cold Atmospheric Plasma

    • Neil D. Almeida, Kenneth Sack, Jonathan H. Sherman

    Pages 289-299

14. Outlook

    • Michael Keidar, Jonathan H. Sherman

    Pages 301-303

15. Back Matter

    Pages 305-310

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This book, written by key researchers in the field, provides a comprehensive analysis and overview of the state of the art of plasma-based cancer therapy. Recent progress in atmospheric plasmas has led to non-thermal or cold atmospheric plasma (CAP) devices with ion temperatures close to room temperature. In contrast to many existing anti-cancer approaches, CAP is a selective anti-cancer modality which has demonstrated significant potential in cancer therapy.

Written by a global, cross-disciplinary group of leading researchers, this book covers basic theory, generation, diagnostics, and simulation of cold atmospheric plasma, as well as their clinical application in cancer therapy, immunotherapy, and future outlook, giving a complete picture of the field.

It is meant for a broad audience, from students to engineers and scientists, who are interested in the emerging world of plasma medical applications. It presents recent advances, primary challenges, and future directions of this exciting, cutting-edge field.

• cold atmospheric plasma
• plasma cancer therapy
• plasma selectivity
• plasma immuno-oncology
• selective anti-cancer modality
• plasma medical application
• plasma clinical application
• plasma cancer diagnostic
• plasma activated media
• plasma cell interaction simulation

• A. James Clark Professor of Engineering Mechanical and Aerospace Engineering School of Engineering and Applied Science, The George Washington University, Washington, DC, USA

  Michael Keidar

Michael Keidar is the A. James Clark Professor of Engineering at the George Washington University. His research concerns plasma medicine, advanced spacecraft propulsion, and plasma-based nanotechnology. He has authored over 280 journal articles, over 290 papers in refereed conference proceedings, 3 books, 2 book chapters, and 12 patents. He received the 2017 Davidson Award in Plasma Physics, and in 2016 he received the American Institute of Astronautics and Aeronautics (AIAA) Engineer of the Year Award for his work on micropropulsion, which resulted in the successful launch of a nanosatellite with plasma thrusters developed by his laboratory.

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