Overview
- Provides a comprehensive overview of the state-of-the-art research on the role of hematopoietic components in tumor development and progression
- Discusses the role of eosinophils, NK cells, ?d T cells, regulatory T Cells, Langerhans cells, Mast cells, B cells and Microglia, and more in the tumor microenvironment
- Illustrates the functional interaction of hematopoietic stem cells with tumor cells
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1273)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Revealing essential roles of the tumor microenvironment in cancer progression, this book focuses on the role of hematopoietic components of the tumor microenvironment. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include eosinophils, NK cells, γδ T cells, regulatory T Cells, Langerhans cells, hematopoietic stem cells, Mast cells, B cells and Microglia, and more.
Taken alongside its companion volumes, Tumor Microenvironment: Hematopoietic Cells – Part B updates us on what we know about various aspects of the tumor microenvironment as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
Editors and Affiliations
About the editor
Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA). He is the Editor-in-Chief of Current Tissue Microenvironment Reports, and associate editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.
Bibliographic Information
Book Title: Tumor Microenvironment
Book Subtitle: Hematopoietic Cells – Part B
Editors: Alexander Birbrair
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-49270-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-49269-4Published: 30 October 2020
Softcover ISBN: 978-3-030-49272-4Published: 30 October 2021
eBook ISBN: 978-3-030-49270-0Published: 29 October 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIV, 215
Number of Illustrations: 2 b/w illustrations, 24 illustrations in colour
Topics: Cancer Research, Immunology, Cell Biology