Tumor Microenvironment

1. Front Matter

   Pages i-xiii

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2. Neuregulin Signaling in the Tumor Microenvironment

   • Ruxue Jia, Hu Zhao, Shuiliang Wang

   Pages 1-29

3. HGF/c-Met Signalling in the Tumor Microenvironment

   • Alberto Zambelli, Giuseppe Biamonti, Angela Amato

   Pages 31-44

4. Eph/Ephrin Signaling in the Tumor Microenvironment

   • Katsuaki Ieguchi, Yoshiro Maru

   Pages 45-56

5. SRC Signaling in Cancer and Tumor Microenvironment

   • Ayse Caner, Elif Asik, Bulent Ozpolat

   Pages 57-71

6. Purinergic Signaling Within the Tumor Microenvironment

   • Dobrin Draganov, Peter P. Lee

   Pages 73-87

7. TGFβ Signaling in the Tumor Microenvironment

   • Cassandra Ringuette Goulet, Frédéric Pouliot

   Pages 89-105

8. Wnt Signaling in the Tumor Microenvironment

   • Yongsheng Ruan, Heather Ogana, Eunji Gang, Hye Na Kim, Yong-Mi Kim

   Pages 107-121

9. Lysophospholipid Signalling and the Tumour Microenvironment

   • Wayne Ng, Andrew Morokoff

   Pages 123-144

10. Adenosine Signaling in the Tumor Microenvironment

    • Luca Antonioli, Matteo Fornai, Carolina Pellegrini, Vanessa D’Antongiovanni, Roberta Turiello, Silvana Morello et al.

    Pages 145-167

11. Androgen Signaling in the Tumor Microenvironment

    • Berna C. Özdemir

    Pages 169-183

12. Back Matter

    Pages 185-191

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Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more.

Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

• Estrogen signaling tumor microenvironment
• estrogen tumor
• RANK signaling tumor microenvironment
• Neuropilins signaling tumor microenvironment
• Eph/ephrin signaling tumor
• Rho-ROCK signaling tumor
• mTOR Signaling Tumor Microenvironment
• Renin-angiotensin system tumor
• Nitric Oxide signaling tumor
• Interferon signaling tumor microenvironment
• Frizzled4 signaling tumor microenvironment
• nitric oxide signaling tumor
• toll receptor signaling tumor

• Department of Radiology, Columbia University Medical Center, New York, NY, USA, Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Brazil

  Alexander Birbrair

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA). He is the Editor-in-Chief of Current Tissue Microenvironment Reports, and associate editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

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