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Advances in Experimental Medicine and Biology

Notch Signaling in Embryology and Cancer

Notch Signaling in Embryology

Editors: Reichrath, Jörg, Reichrath, Sandra (Eds.)

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  • Presents content in a logical and coherent structure, enabling the reader to readily access relevant information
  • Edited by renowned experts on Notch and Notch Signaling with contributions from internationally-recognized researchersTimely and urgently needed update in a rapidly developing field
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eBook 117,69 €
price for France (gross)
  • ISBN 978-3-030-34436-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 147,69 €
price for France (gross)
  • ISBN 978-3-030-34435-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.

Taken as a whole, with its companion books – Molecular Biology of Notch Signaling and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors.  Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students. 

About the authors

Sandra and Jörg Reichrath are working at the Clinic for Dermatology; Allergology and Venerology of the Saarland University Hospital in Homburg/Saar. Germany. Main research interests include photobiology, carcinogenesis of skin cancer (with a special interest for the role of ultraviolet radiation, Notch and p53), and the relevance of the vitamin D endocrine system for health and disease. Sandra received her academic degrees (Dipl. Biol. and Dr. rer. nat.) from the Albert-Ludwigs-Universität (Freiburg, Germany) and from Saarland University (Saarbrücken/Homburg, Germany), respectively. Jörg received his academic degrees (Dr. med., venia legendi) from Saarland University (Saarbrücken/Homburg, Germany). He has been awarded numerous prizes including the Arnold-Rikli-Prize in 2006.

Table of contents (9 chapters)

Table of contents (9 chapters)
  • Notch Signaling and Tissue Patterning in Embryology: An Introduction

    Pages 1-7

    Reichrath, Jörg (et al.)

  • Notch Signaling and Embryonic Development: An Ancient Friend, Revisited

    Pages 9-37

    Reichrath, Jörg (et al.)

  • The Five Faces of Notch Signalling During Drosophila melanogaster Embryonic CNS Development

    Pages 39-58

    Bahrampour, Shahrzad (et al.)

  • Epigenetic Regulation of Notch Signaling During Drosophila Development

    Pages 59-75

    Wei, Chuanxian (et al.)

  • Regulation of Proneural Wave Propagation Through a Combination of Notch-Mediated Lateral Inhibition and EGF-Mediated Reaction Diffusion

    Pages 77-91

    Sato, Makoto (et al.)

Buy this book

eBook 117,69 €
price for France (gross)
  • ISBN 978-3-030-34436-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 147,69 €
price for France (gross)
  • ISBN 978-3-030-34435-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Notch Signaling in Embryology and Cancer
Book Subtitle
Notch Signaling in Embryology
Editors
  • Jörg Reichrath
  • Sandra Reichrath
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1218
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-34436-8
DOI
10.1007/978-3-030-34436-8
Hardcover ISBN
978-3-030-34435-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 195
Number of Illustrations
11 b/w illustrations, 5 illustrations in colour
Topics