Overview
- Presents content in a logical and coherent structure, enabling the reader to readily access relevant information
- Edited by renowned experts on Notch and Notch Signaling with contributions from internationally-recognized researchers
- Timely and urgently needed update in a rapidly developing field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1218)
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.
Taken as a whole, with its companion books – Molecular Biology of Notch Signaling and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
Editors and Affiliations
About the editors
Sandra and Jörg Reichrath are working at the Clinic for Dermatology; Allergology and Venerology of the Saarland University Hospital in Homburg/Saar. Germany. Main research interests include photobiology, carcinogenesis of skin cancer (with a special interest for the role of ultraviolet radiation, Notch and p53), and the relevance of the vitamin D endocrine system for health and disease. Sandra received her academic degrees (Dipl. Biol. and Dr. rer. nat.) from the Albert-Ludwigs-Universität (Freiburg, Germany) and from Saarland University (Saarbrücken/Homburg, Germany), respectively. Jörg received his academic degrees (Dr. med., venia legendi) from Saarland University (Saarbrücken/Homburg, Germany). He has been awarded numerous prizes including the Arnold-Rikli-Prize in 2006.
Bibliographic Information
Book Title: Notch Signaling in Embryology and Cancer
Book Subtitle: Notch Signaling in Embryology
Editors: Jörg Reichrath, Sandra Reichrath
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-34436-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-34435-1Published: 15 February 2020
Softcover ISBN: 978-3-030-34438-2Published: 15 February 2021
eBook ISBN: 978-3-030-34436-8Published: 14 February 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XIII, 195
Number of Illustrations: 11 b/w illustrations, 5 illustrations in colour
Topics: Cancer Research, Cell Biology, Embryology