Oral Mucosal Immunity and Microbiome

1. Front Matter

   Pages i-xii

   PDF

2. Advances in Oral Mucosal Immunity and the Microbiome

   • Georgios N. Belibasakis, George Hajishengallis

   Pages 1-9

3. Trained Innate Immunity and Its Implications for Mucosal Immunity and Inflammation

   • George Hajishengallis, Xiaofei Li, Ioannis Mitroulis, Triantafyllos Chavakis

   Pages 11-26

4. Signaling Systems in Oral Bacteria

   • Daniel P. Miller, Richard J. Lamont

   Pages 27-43

5. Origin of Th17 Cells in Type 2 Diabetes-Potentiated Periodontal Disease

   • Barbara S. Nikolajczyk, Dolphus R. Dawson III

   Pages 45-54

6. Gingival Epithelial Cell Recognition of Lipopolysaccharide

   • Nutthapong Kantrong, Thao T. To, Richard P. Darveau

   Pages 55-67

7. The Relationship of Candida albicans with the Oral Bacterial Microbiome in Health and Disease

   • Martinna Bertolini, Anna Dongari-Bagtzoglou

   Pages 69-78

8. A Potential Role of Phospholipase 2 Group IIA (PLA₂-IIA) in P. gingivalis-Induced Oral Dysbiosis

   • Octavio A. Gonzalez, Vanessa Euzebio-Alves, Yelena Alimova, Ahmad Al-Attar, J. L. Ebersole

   Pages 79-95

9. Helicobacter spp. in Experimental Models of Colitis

   • Christoph Mueller, Cheong K. C. Kwong Chung, Martin R. Faderl, Jennifer Brasseit, Daniel Zysset

   Pages 97-105

10. T Helper 17 Cells as Pathogenic Drivers of Periodontitis

    • Nicolas Dutzan, Loreto Abusleme

    Pages 107-117

11. Candida–Bacterial Biofilms and Host–Microbe Interactions in Oral Diseases

    • Thais de Cássia Negrini, Hyun Koo, Rodrigo Alex Arthur

    Pages 119-141

12. Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging

    • J. L. Ebersole, L. Orraca, M. J. Novak, S. Kirakodu, J. Gonzalez-Martinez, O. A. Gonzalez

    Pages 143-163

13. Neutrophil Interaction with Emerging Oral Pathogens: A Novel View of the Disease Paradigm

    • Irina Miralda, Aruna Vashishta, Silvia M. Uriarte

    Pages 165-178

14. Biologically Defined or Biologically Informed Traits Are More Heritable Than Clinically Defined Ones: The Case of Oral and Dental Phenotypes

    • Cary S. Agler, Kevin Moss, Kamaira H. Philips, Julie T. Marchesan, Miguel Simancas-Pallares, James D. Beck et al.

    Pages 179-189

The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems.

In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk. 

• oral immunity
• oral microbiome
• periodontal disease
• mucosal immunity
• host immunity
• Systems Biology

• Division of Oral Diseases, Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden

  Georgios N. Belibasakis, Nagihan Bostanci

• Department of Microbiology, University of Pennsylvania, Penn Dental Medicine, Philadelphia, USA

  George Hajishengallis

• King’s College London Dental Institute, London, UK

  Michael A. Curtis

Georgios N. Belibasakis
Karolinska Institute Department of Dental Medicine
Department of Dental Medicine
Huddinge
Stockholms Län
Sweden


Nagihan Bostanci
Karolinska Institute Department of Dental Medicine
Huddinge
Stockholms Län
Sweden


Michael A. Curtis
King's College London Dental Institute
London
United Kingdom


George Hajishengallis
Univ of Pennsylvania Penn Dental Med Microbio
Penn Dental Med Microbio
Philadelphia
Pennsylvania
USA

Policies and ethics