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Difficult To Treat Asthma

Clinical Essentials

  • Book
  • © 2020

Overview

  • Details difficult to treat asthma, its difference from severe asthma, and clinical management guidelines
  • Contains clinical pearls from leading asthma experts that can be used as a quick bedside reference
  • Key points illustrate application of major principles covered

Part of the book series: Respiratory Medicine (RM)

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Table of contents (16 chapters)

Keywords

About this book

This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat’. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. 
 
This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art’ reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach.  This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.  

Reviews

 

Editors and Affiliations

  • Mary Parkes Center for Asthma, Allergy & Pulmonary Care, University of Rochester School of Medicine, Rochester, USA

    Sandhya Khurana

  • Asthma Clinical & Research Programs Pulmonary Sciences and Critical Care, University of Colorado, Denver, USA

    Fernando Holguin

About the editors

Sandhya Khurana, MD is an Associate Professor of Medicine at the University of Rochester and the Co-Director of Mary Parkes Center for Asthma, Allergy & Pulmonary Care. Dr. Khurana is an adult pulmonologist with a specialized focus in management of severe and difficult to treat asthma. She is the immediate past chair of the Airways Disorders NetWork of the American College of Chest Physicians. Dr. Khurana has chaired asthma-focused sessions and participated as faculty at national and international meetings. She also serves on the American Thoracic Society and European Respiratory Society joint taskforce on severe asthma. 

Fernando Holguin, MD., MPH., is Professor of Medicine and Pediatrics and the Director of the Asthma Clinical and Research Programs at the University of Colorado. Dr Holguin has been involved in asthma clinical and translational research for over 20 years. His research work primarily focuses on the intersection of obesity and asthma. Dr. Holguin co-chairs the American Thoracic Society and European Respiratory Society taskforce on Severe Asthma. 

Bibliographic Information

  • Book Title: Difficult To Treat Asthma

  • Book Subtitle: Clinical Essentials

  • Editors: Sandhya Khurana, Fernando Holguin

  • Series Title: Respiratory Medicine

  • DOI: https://doi.org/10.1007/978-3-030-20812-7

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-20811-0Published: 25 September 2019

  • Softcover ISBN: 978-3-030-20814-1Published: 25 September 2020

  • eBook ISBN: 978-3-030-20812-7Published: 29 August 2019

  • Series ISSN: 2197-7372

  • Series E-ISSN: 2197-7380

  • Edition Number: 1

  • Number of Pages: XV, 334

  • Number of Illustrations: 3 b/w illustrations, 27 illustrations in colour

  • Topics: Pneumology/Respiratory System, Primary Care Medicine

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