- Includes cutting-edge methods and protocols for the study of chromothripsis
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
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- About this book
-
This detailed book presents an up-to-date view on methods and experimental approaches developed to identify and explore the chromothripsis phenomenon. Beginning with a section exploring the genesis and impact of chromothripsis, the collection continues by covering the identification of chromothripsis, the causal mechanisms of chromothripsis, the bioinformatics tools for chromothripsis analysis, and experimental systems recently developed for the in vitro investigation of chromothripsis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Chromothripsis: Methods and Protocols serves as a vital resource for cell biologists, molecular biologists, cytogeneticists, and geneticists investigating chromothripsis, but also for students and researchers new to the field of chromothripsis and genomic instability.
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Bibliographic Information
- Bibliographic Information
-
- Book Title
- Chromothripsis
- Book Subtitle
- Methods and Protocols
- Editors
-
- Franck Pellestor
- Series Title
- Methods in Molecular Biology
- Series Volume
- 1769
- Copyright
- 2018
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC, part of Springer Nature
- eBook ISBN
- 978-1-4939-7780-2
- DOI
- 10.1007/978-1-4939-7780-2
- Hardcover ISBN
- 978-1-4939-7779-6
- Series ISSN
- 1064-3745
- Edition Number
- 1
- Number of Pages
- XI, 367
- Number of Illustrations
- 12 b/w illustrations, 73 illustrations in colour
- Topics
