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Methods in Molecular Biology

Mitosis

Methods and Protocols

Editors: Sharp, David J. (Ed.)

  • Presents current up-to-date methodologies
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook 89,24 €
price for France (gross)
  • ISBN 978-1-4939-0329-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 126,59 €
price for France (gross)
  • ISBN 978-1-4939-0328-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover 110,76 €
price for France (gross)
  • ISBN 978-1-4939-4301-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Mitosis: Methods and Protocols provides state-of-the-art overviews on the most important approaches currently used in mitosis research spanning from the analysis of single molecules in isolation to their utilization within the complex environment of the cell. The volume is divided into four parts, each focused on methods pertaining to distinct aspects of mitosis research. Part I presents approaches for visualizing and analyzing the dynamic behaviors of the spindle apparatus, the microtubule based machine that drives chromosome segregation. Part II focuses more generally on methods for studying and manipulating the microtubule cytoskeleton in cells and complex cell free extracts. Part III provides state of the art biophysical and high resolution microscopy approaches for assessing complex interactions between microtubules and microtubule-associated proteins in isolation as well as microtubule structure in cells. Part IV provides methods for studying the effects of cell shape on cell division and methods for quantifying aneuploidy (aberrant chromosome number) which frequently results from mitotic defects and has been linked to human maladies ranging from birth defects to cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Mitosis: Methods and Protocols seeks to provide diverse methods and new techniques to address new or old questions related to the mechanisms of mitosis.

Table of contents (14 chapters)

  • Analysis of Mitotic Protein Dynamics and Function in Drosophila Embryos by Live Cell Imaging and Quantitative Modeling

    Brust-Mascher, Ingrid (et al.)

    Pages 3-30

    Preview Buy Chapter 47,94 €
  • Rapid Measurement of Mitotic Spindle Orientation in Cultured Mammalian Cells

    Decarreau, Justin (et al.)

    Pages 31-40

    Preview Buy Chapter 47,94 €
  • Automated Segmentation of the First Mitotic Spindle in Differential Interference Contrast Microcopy Images of C. elegans Embryos

    Farhadifar, Reza (et al.)

    Pages 41-45

    Preview Buy Chapter 47,94 €
  • Imaging the Mitotic Spindle by Spinning Disk Microscopy in Tobacco Suspension Cultured Cells

    Murata, Takashi (et al.)

    Pages 47-55

    Preview Buy Chapter 47,94 €
  • Image-Based Computational Tracking and Analysis of Spindle Protein Dynamics

    Yang, Ge

    Pages 57-78

    Preview Buy Chapter 47,94 €

Buy this book

eBook 89,24 €
price for France (gross)
  • ISBN 978-1-4939-0329-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 126,59 €
price for France (gross)
  • ISBN 978-1-4939-0328-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover 110,76 €
price for France (gross)
  • ISBN 978-1-4939-4301-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mitosis
Book Subtitle
Methods and Protocols
Editors
  • David J. Sharp
Series Title
Methods in Molecular Biology
Series Volume
1136
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, New York
eBook ISBN
978-1-4939-0329-0
DOI
10.1007/978-1-4939-0329-0
Hardcover ISBN
978-1-4939-0328-3
Softcover ISBN
978-1-4939-4301-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 308
Number of Illustrations
12 b/w illustrations, 71 illustrations in colour
Topics