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Neurodegenerative Diseases Biomarkers

Towards Translating Research to Clinical Practice

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 173)

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Table of contents (21 protocols)

  1. Front Matter

    Pages i-xviii
  2. Introduction

    1. Front Matter

      Pages 1-1
    2. Prevalence, Needs , Strategies , and Risk Factors for Neurodegenerative Diseases

      • Philip V. Peplow, Bridget Martinez, Thomas A. Gennarelli
      Pages 3-8
  3. Research Methods

    1. Front Matter

      Pages 9-9
    2. Activation of Microglia and Macrophages in Neurodegenerative Diseases

      • Anna Salamero-Boix, Michael Schulz, Lisa Sevenich
      Pages 11-38
    3. Tau Pathology in Neurodegenerative Diseases

      • Thomas Vogels, Tomáš Hromádka
      Pages 71-97
    4. Role of SIRT3 and Mitochondrial Dysfunction in Neurodegeneration

      • Jin-Hui Hor, Munirah Mohamad Santosa, Shi-Yan Ng
      Pages 99-120
    5. Oxidative Stress and Cellular Dysfunction in Neurodegenerative Disease

      • Anju Singh, Ritushree Kukreti, Shrikant Kukreti
      Pages 121-154
    6. Biomarkers in Parkinson’s Disease

      • Andrei Surguchov
      Pages 155-180
    7. Metabolomic Biomarkers in Parkinson’s Disease

      • Yaping Shao, Xiaojiao Xu, Nanxing Wang, Guowang Xu, Weidong Le
      Pages 181-213
    8. Neuroinflammation in Huntington’s Disease

      • John D. Lee, Martin W. Lo, Jenny N. T. Fung, Trent M. Woodruff
      Pages 215-233
    9. Biomarkers in Huntington’s Disease

      • Annie Killoran
      Pages 235-262
    10. Biofluid Biomarkers of Amyotrophic Lateral Sclerosis

      • Cory J. Holdom, Frederik J. Steyn, Robert D. Henderson, Pamela A. McCombe, Mary-Louise Rogers, Shyuan T. Ngo
      Pages 263-306
    11. Impedimetric Immunosensing for Neuroinflammatory Biomarker Profiling

      • Andrea Cruz, Catarina M. Abreu, Paulo P. Freitas, Inês Mendes Pinto
      Pages 347-359
  4. Clinical Methods

    1. Front Matter

      Pages 405-405

About this book

This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. 

Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.



Editors and Affiliations

  • Department of Anatomy, University of Otago, Dunedin, New Zealand

    Philip V. Peplow

  • Department of Pharmacology, Department of Medicine, Reno School of Medicine, University of Nevada, Reno, USA

    Bridget Martinez

  • Department of Neurosurgery, George Washington University, West Chester, USA

    Thomas A. Gennarelli

Bibliographic Information

  • Book Title: Neurodegenerative Diseases Biomarkers

  • Book Subtitle: Towards Translating Research to Clinical Practice

  • Editors: Philip V. Peplow, Bridget Martinez, Thomas A. Gennarelli

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-1712-0

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2022

  • Hardcover ISBN: 978-1-0716-1711-3Published: 16 October 2021

  • Softcover ISBN: 978-1-0716-1714-4Published: 16 October 2022

  • eBook ISBN: 978-1-0716-1712-0Published: 15 October 2021

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVIII, 565

  • Number of Illustrations: 6 b/w illustrations, 42 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access