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CPP, Cell-Penetrating Peptides

Authors:

  • Provides a comprehensive update of cell penetrating peptides (CPP)
  • Summarizes the CPP uptake mechanisms and their critical analysis
  • Shows methods used for CPP studies and applications

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. Introduction

    • Ülo Langel
    Pages 1-28
  3. Methods for CPP Functionalization

    • Ülo Langel
    Pages 83-156
  4. Protein Delivery and Mimicry

    • Ülo Langel
    Pages 157-193
  5. Targeting Strategies

    • Ülo Langel
    Pages 195-263
  6. Methods for Structural Studies of CPPs

    • Ülo Langel
    Pages 289-323
  7. Kinetics of CPPs Cellular Uptake

    • Ülo Langel
    Pages 325-337
  8. Toxicity and Immune Response

    • Ülo Langel
    Pages 339-357
  9. Cell-Translocation Mechanisms of CPPs

    • Ülo Langel
    Pages 359-394
  10. Therapeutic Potential of CPPs

    • Ülo Langel
    Pages 409-461
  11. Back Matter

    Pages 463-470

About this book

In this book, a summary and update of the most important areas of CPP research are presented, whilst  raising relevant questions for further development. 

The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. 

The monograph is written for researchers and students in the field.


Authors and Affiliations

  • Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

    Ülo Langel

Bibliographic Information

  • Book Title: CPP, Cell-Penetrating Peptides

  • Authors: Ülo Langel

  • DOI: https://doi.org/10.1007/978-981-13-8747-0

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Softcover ISBN: 978-981-13-8749-4Published: 14 August 2020

  • eBook ISBN: 978-981-13-8747-0Published: 03 June 2019

  • Edition Number: 1

  • Number of Pages: XII, 470

  • Number of Illustrations: 8 b/w illustrations, 17 illustrations in colour

  • Topics: Protein Science, Molecular Medicine, Medicinal Chemistry

Buy it now

Buying options

eBook USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access