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Natural Bio-active Compounds

Volume 2: Chemistry, Pharmacology and Health Care Practices

  • Elaborates major classes of compounds like alkaloids, tannins, saponins, lignin, glycosides, and terpenoids, which are integral part of plant-microbe interactions for adapting to environmental irregularities
  • Describes the chemistry of bioactive plant secondary metabolites, their production and pharmacological properties, as well as biotechnological approaches to tackling various human diseases
  • Offers a valuable asset for all students, educators, and healthcare professionals involved in medicinal plant cultivation, plant tissue culture, in vitro production of secondary metabolites, and therapeutic research

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xx
  2. The Role of Plant Metabolites in Drug Discovery: Current Challenges and Future Perspectives

    • Nooryasmin Anwar, Yong Kiat Teo, Joash Ban Lee Tan
    Pages 25-51
  3. Myristica fragrans Houtt.: Botanical, Pharmacological, and Toxicological Aspects

    • Greetha Arumugam, Boregowda Purushotham, Mallappa Kumara Swamy
    Pages 81-106
  4. Coscinium fenestratum: A Review on Phytochemicals and Pharmacological Properties

    • Muhammad Taher, Mohamad Shahreen Amri, Deny Susanti, Muhammad Badri Abdul Kudos, Anis Natasha Shafawi, Soraya Nur Yazid
    Pages 107-125
  5. Curcumin-Loaded Nanoparticles and Their Potential as Anticancer Agents in Breast Cancer

    • Leanne De Silva, Bey-Hing Goh, Learn-Han Lee, Lay-Hong Chuah
    Pages 147-178
  6. Techniques for Extraction, Isolation, and Standardization of Bio-active Compounds from Medicinal Plants

    • Mohammad Kamil Hussain, Mohammad Saquib, Mohammad Faheem Khan
    Pages 179-200
  7. Phytotherapeutics: The Substitutes for Glioblastoma Multiforme

    • Megha Gautam, Sahil Srivastav, Niharika Tiwary, Shweta Dang, Reema Gabrani
    Pages 201-213
  8. Cosmetic Potential of Natural Products: Industrial Applications

    • Mahesh Sreekantan Krishna, Fathima Jaseela, Veena Vijayan Girija
    Pages 215-250
  9. Plant Metabolites as New Leads to Drug Discovery

    • Santanu Sasidharan, Prakash Saudagar
    Pages 275-295
  10. Therapeutic Potential of Plant Polyphenolics and Their Mechanistic Action Against Various Diseases

    • Rajeswari Ravindran, Mallappa Kumara Swamy, Ravindran Jaganathan
    Pages 313-351
  11. Bio-active Compounds from Unani Medicinal Plants and Their Application in Urolithiasis

    • Shaikh Ajij Ahmed Makbul, Nasreen Jahan, Mohd Afsahul Kalam
    Pages 369-407
  12. Therapeutic Potential of Rhizomatous Plants Used in Unani Medicare System

    • Mohd Afsahul Kalam, Ghufran Ahmad, Anwar Shahzad, Shaikh Ajij Ahmad Maqbul, Mohd Sayeed Akhtar
    Pages 409-464
  13. Extraction Techniques for Plant-Based Bio-active Compounds

    • Perihan Yolci Omeroglu, Büşra Acoglu, TuÄŸba Özdal, Canan Ece Tamer, Ömer Utku Çopur
    Pages 465-492

About this book

Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry, nature remains an essential resource for drug discovery.


Therefore, more and more researchers are interested in understanding the chemistry, clinical pharmacology, and beneficial effects of bioactive compounds in connection with solving human health problems. This book presents a wealth of information on natural metabolites that have been or are currently being used as drugs or leads for the discovery of new drugs. In addition, it highlights the importance of natural products against various human diseases, and their applications in the drug, nutraceuticals, cosmetics and herbal industries. Accordingly, the book offers a valuable resource for all students, educators, and healthcare experts involved in natural product research, phytochemistry, and pharmacological research. 

Editors and Affiliations

  • Department of Biotechnology, East West First Grade College of Science, Bengaluru, India

    Mallappa Kumara Swamy

  • Department of Botany, Gandhi Faiz-e-Aam College, Shahjahanpur, India

    Mohd Sayeed Akhtar

About the editors

Dr. Mohd Sayeed Akhtar (PhD) is an Assistant Professor at Gandhi Faiz-e-Aam College, Shahjahanpur, UP, India. He received his PhD degree from Aligarh Muslim University (AMU), India in 2008, prior to conducting post-doctoral research at the Botanical Institute, University of Basel (BIB), Switzerland (2008–2010), and at Chonbuk National University (CBNU), Republic of Korea in 2011. He was an Assistant Professor at Jimma University, Ethiopia (2011-2014), and a fellow researcher at the Institute of Tropical Agriculture, Universiti Putra Malaysia (UPM), (2014-2015). Dr. Akhtar has more than 15 years of research and 10 years of teaching experience in soil microbiology, applied microbiology, environmental microbiology, molecular biology, plant pathology and plant nanobiotechnology. He has authored or co-authored more than one hundred articles in peer-reviewed journals, conference proceedings, and book chapters, and has edited 10 books with international publishers. Further, he serves as an editorial board member and reviewer for several high-impact international journals. His current research is focused on rhizospheric plant-microbe interactions and molecular biotechnology, bioremediation, biomineralization, nano-fertilizers and nanobiotechnology. 


Dr. Mallappa Kumara Swamy (PhD) is a Professor and Head of the Department of Biotechnology at East West College of Science, Bengaluru, Karnataka, India. He completed his postdoctoral research at the Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia. Before that, he had worked as an Associate Professor and Head of the Department of Biotechnology, Padmashree Institute of Management and Sciences, Bangalore University, Bengaluru, India. He received his PhD (Biotechnology) from Acharya Nagarjuna University, Guntur, India in 2013. He has more than 15 years of teaching and research experience in the fields of plant biotechnology, secondary metabolite production, phytochemistry and bioactive studies. Dr. Swamy has authored 80 research publications in peer-reviewed journals and 16 book chapters. Recently, he has edited four books published by Springer Nature Singapore Pte Ltd., Singapore. He also serves as an editorial board member and reviewer for several high-impact international journals. His current research is focused on cell and tissue culture technology for bioactive compound production, and on nanotechnology for medical applications.

Bibliographic Information

  • Book Title: Natural Bio-active Compounds

  • Book Subtitle: Volume 2: Chemistry, Pharmacology and Health Care Practices

  • Editors: Mallappa Kumara Swamy, Mohd Sayeed Akhtar

  • DOI: https://doi.org/10.1007/978-981-13-7205-6

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-13-7204-9Published: 01 October 2019

  • Softcover ISBN: 978-981-13-7207-0Published: 01 October 2020

  • eBook ISBN: 978-981-13-7205-6Published: 19 September 2019

  • Edition Number: 1

  • Number of Pages: XX, 492

  • Number of Illustrations: 25 b/w illustrations, 38 illustrations in colour

  • Topics: Plant Anatomy/Development, Plant Physiology, Plant Biochemistry, Plant Genetics and Genomics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access