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Bioinformatics: Sequences, Structures, Phylogeny

  • Book
  • © 2018

Overview

Editors:
  1. Asheesh Shanker

    1. Department of Bioinformatics, Central University of South Bihar, Gaya, India

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  • Cover the topics from sequencing to structural analysis

  • Beneficial to a beginner as well as for advanced learner

  • Covers intellectual property protection in bioinformatics

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-ix
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  2. Intellectual Property Rights and Bioinformatics: An Introduction

    • Shilpa, Umang Gupta
    Pages 1-14

  3. Next-Generation Sequencing: Technology, Advancements, and Applications

    • Gourja Bansal, Kiran Narta, Manoj Ramesh Teltumbade
    Pages 15-46

  4. Sequence Alignment

    • Benu Atri, Olivier Lichtarge
    Pages 47-69

  5. Understanding Genomic Variations in the Context of Health and Disease: Annotation, Interpretation, and Challenges

    • Ankita Narang, Aniket Bhattacharya, Mitali Mukerji, Debasis Dash
    Pages 71-95

  6. Metagenomics: Focusing on the Haystack

    • Indu Khatri, Meenakshi Anurag
    Pages 97-113

  7. Computational Epigenomics and Its Application in Regulatory Genomics

    • Shalu Jhanwar
    Pages 115-139

  8. Data Mining to Detect Common, Unique, and Polymorphic Simple Sequence Repeats

    • Aditi Kapil, C. K. Jha, Asheesh Shanker
    Pages 141-154

  9. R-Programming for Genome-Wide Data Analysis

    • Arunima Shilpi, Shraddha Dubey
    Pages 155-171

  10. Computational Approaches to Studying Molecular Phylogenetics

    • Benu Atri, Olivier Lichtarge
    Pages 173-190

  11. Structural Bioinformatics: Life Through The 3D Glasses

    • Ankita Punetha, Payel Sarkar, Siddharth Nimkar, Himanshu Sharma, Yoganand KNR, Siranjeevi Nagaraj
    Pages 191-253

  12. A Survey of the Structural Parameters Used for Computational Prediction of Protein Folding Process

    • Gulshan Khalique, Tambi Richa
    Pages 255-270

  13. Quality Assessment of Protein Tertiary Structures: Past, Present, and Future

    • Ankita Singh, Rahul Kaushik, B. Jayaram
    Pages 271-288

  14. Predicting Protein Function Using Homology-Based Methods

    • Swati Sinha, Birgit Eisenhaber, Andrew M. Lynn
    Pages 289-305

  15. Drug Discovery: An In Silico Approach

    • Sukriti Goyal, Salma Jamal, Abhinav Grover, Asheesh Shanker
    Pages 307-328

  16. Advanced In Silico Tools for Designing of Antigenic Epitope as Potential Vaccine Candidates Against Coronavirus

    • Mehak Dangi, Rinku Kumari, Bharat Singh, Anil Kumar Chhillar
    Pages 329-357

  17. Machine Learning: What, Why, and How?

    • Salma Jamal, Sukriti Goyal, Abhinav Grover, Asheesh Shanker
    Pages 359-374

  18. Command-Line Tools in Linux for Handling Large Data Files

    • Deepti Mishra, Garima Khandelwal
    Pages 375-392

  19. Back Matter

    Pages 393-402
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Keywords

About this book

This book provides a comprehensive overview of the concepts and approaches used for sequence, structure, and phylogenetic analysis. Starting with an introduction to the subject and intellectual property protection for bioinformatics, it guides readers through the latest sequencing technologies, sequence analysis, genomic variations, metagenomics, epigenomics, molecular evolution and phylogenetics, structural bioinformatics, protein folding, structure analysis and validation, drug discovery, reverse vaccinology, machine learning, application of R programming in biological data analysis, and the use of Linux in handling large data files.

Editors and Affiliations

  • Department of Bioinformatics, Central University of South Bihar, Gaya, India

    Asheesh Shanker

About the editor

Dr. Asheesh Shanker is Associate Professor and Coordinator of the Bioinformatics Programme at the Centre for Biological Sciences, Central University of South Bihar, India. Prior to that he served as an Assistant/Associate Professor (2004-2015) at the Department of Bioscience and Biotechnology, Banasthali Vidyapith, Rajasthan, India, and he has a decade of teaching and research experience. His research focuses on data mining, database and server development, evolutionary analysis, computational genomics, and structure analysis. He is a recipient of prestigious Indo-Swiss Joint Research Programme fellowship from the University of Lausanne, Switzerland. He has been a convener/organizing secretary for several national bioinformatics workshops, served as a member of organizing committee of International conferences, and delivered invited talks. He is also a reviewer for a number of peer-reviewed journals. He has published more than 50 research articles in leading national and international journals and authored/co-authored 3 books in the field of bioinformatics, which are popular among students.


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