Progress in Drug Research

Systems Biological Approaches in Infectious Diseases

Herausgeber: Boshoff, Helena I., Barry, Clifton E. (Eds.)

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Über dieses Buch

Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the "omic" sciences are computed and used to build in silico models of biological systems that ultimately will prove to be an invaluable tool in drug development.

This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identification of drug targets. It includes practical examples from the various "omic" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment, as well as those in the academic field with an interest in the functional application of the "omic" sciences.

Inhaltsverzeichnis (12 Kapitel)

Inhaltsverzeichnis (12 Kapitel)
  • Systems biology and its impact on anti-infective drug development

    Seiten 1-20

    Stumpf, Michael P. (et al.)

  • Applications of transcriptional profiling in antibiotics discovery and development

    Seiten 21-47

    Fischer, Hans Peter (et al.)

  • Chemical genetics: An evolving toolbox for target identification and lead optimization

    Seiten 49-77

    Boshoff, Helena I. (et al.)

  • Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action

    Seiten 79-101

    Bandow, Julia E. (et al.)

  • Elucidating the mode-of-action of compounds from metabolite profiling studies

    Seiten 103-129

    Højer-Pedersen, Jesper (et al.)

Dieses Buch kaufen

eBook 203,29 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-7643-7567-6
  • Versehen mit digitalem Wasserzeichen, DRM-frei
  • Erhältliche Formate: PDF
  • eBooks sind auf allen Endgeräten nutzbar
  • Sofortiger eBook Download nach Kauf
Hardcover 256,80 €
Preis für Deutschland (Brutto)
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Bibliografische Information

Bibliographic Information
Buchtitel
Systems Biological Approaches in Infectious Diseases
Herausgeber
  • Helena I. Boshoff
  • Clifton E. Barry
Titel der Buchreihe
Progress in Drug Research
Buchreihen Band
64
Copyright
2007
Verlag
Birkhäuser Basel
Copyright Inhaber
Birkhäuser Basel
eBook ISBN
978-3-7643-7567-6
DOI
10.1007/978-3-7643-7567-6
Hardcover ISBN
978-3-7643-7566-9
Buchreihen ISSN
0071-786X
Auflage
1
Seitenzahl
IX, 350
Themen