Cellular Metabolism of the Arterial Wall and Central Nervous System

1. Front Matter

   Pages I-XI

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2. Elementary Steps in Synaptic Transmission Revealed by Currents Through Single Ion Channels

   • Bert Sakmann

   Pages 1-34

3. Molecular Biology and Pathology of Alzheimer’s Disease

   • Konrad Beyreuther, Gerd Multhaup, Colin L. Masters

   Pages 35-54

4. The Function of Oligodendrocytes in the Maturation of the Brain

   • Wilhelm Stoffel

   Pages 55-76

5. Biopsy Approach to the Study and Diagnosis of Inborn Errors of Metabolism Affecting the Brain

   • M. Daria Haust

   Pages 77-87

6. The Molecular Basis of Genetic Defects in HDL Metabolism

   • H. Bryan Brewer, Daniel J. Rader, Hanns-Georg Klein, Katsunori Ikewaki, Silvia Santamarina-Fojo

   Pages 89-104

7. Lipoprotein Receptor-Mediated Oocyte Growth

   • Wolfgang J. Schneider, Amandio Vieira, Ian MacLachlan, Johannes Nimpf

   Pages 105-115

8. A New Pathway of Phospholipid Biosynthesis in Animal Cells

   • John A. Glomset

   Pages 117-126

9. How Important is Lp(a) for a Clinical Decision?

   • Dietrich Seidel

   Pages 127-137

10. Genetic Variation of the Apolipoprotein(a) Gene and Coronary Heart Disease

    • Gerd Utermann

    Pages 139-158

11. The HMG-CoA Reductase Inhibitors Story

    • Akira Endo

    Pages 159-166

12. LDL Receptor-Dependent Polyunsaturated Fatty Acid Transport and Metabolism

    • Andreas J. R. Habenicht, Peter Salbach, Uwe Janßen-Timmen

    Pages 167-178

13. Receptor Mediated Hepatic Uptake of Lipoproteins

    • Stefan Jäckle, Franz Rinninger, Jobst Greeve, Ulrike Beisiegel, Eberhard Windler, Heiner Greten

    Pages 179-191

14. Common Mutations Underlying the Hypertriglyceridaemia/Low HDL Syndrome

    • David J. Galton

    Pages 193-207

15. Triglycerides, HDL, and Atherosclerosis

    • Josef R. Patsch

    Pages 209-215

16. Studies on Lipoprotein Lipase

    • Olga Stein, Gideon Friedman, Yechezkiel Stein

    Pages 217-221

17. Smoking, Lipoproteins and Coronary Heart Disease - Is there a Link?

    • Yechezkiel Stein, Olga Stein

    Pages 223-231

18. Biochemical and Molecular Characterization of the Scavenger Receptors

    • Hans Alois Dresel

    Pages 233-244

19. Cellular Interactions in Atherogenesis

    • Eberhard von Hodenberg, Eva Pestel, Martina Hautmann, Jörg Kreuzer, Christoph Bode, Wolfgang Kübler

    Pages 245-253

20. HMGCoA Reductase Enzyme Inhibitors Effects on Proliferation of Arterial Myocytes

    • M. R. Soma, E. Doneffi, V. Dimitri, A. Corsini, R. Paoletti

    Pages 255-263

International experts review the molecular biology of ion channels, diseases of the central nervous system including Alzheimer's disease, the molecular biology of atherogenesis, plasma lipproteins, lipid transport, long chain fatty acid transport and metabolism, and lipoprotein receptors. Future directions and perspectives and common features in these important areas are discussed.

• Activation
• biosynthesis
• cardiovascular
• genes
• molecular biology
• proteins
• metabolic disease

• Heidelberger Akademie der Wissenschaften, Heidelberg, Germany

  Gotthard Schettler

• Universitäts-Krankenhaus Eppendorf, Hamburg 20, Germany

  Heiner Greten

• Abt. Innere Medizin I, Medizinische Universitätsklinik, Heidelberg, Germany

  Andreas J. R. Habenicht

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