Overview
- Gives a comprehensive and up to date overview on the field
- Written by experts in the field
- Covers the role of ECM in development from all angles
- Includes supplementary material: sn.pub/extras
Part of the book series: Biology of Extracellular Matrix (BEM)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (9 chapters)
-
Front Matter
-
Informational Signals in Extracellular Matrix and Matrix Influences on Cell Movement in the Developing Embryo
-
Front Matter
-
-
Extracellular Matrix-Direct Morphogenesis, Growth Factor Signaling, and Maintenance of the Stem Cell Niche
-
Front Matter
-
-
Extracellular Matrix-Direct Morphogenesis, Growth Factor Signaling, and Maintenance of the Stem Cell Niche
-
Model Organisms and the Lexicon of Developmental Signals Associated with the Extracellular Matrix
-
Front Matter
-
-
Back Matter
Keywords
About this book
Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.
Editors and Affiliations
Bibliographic Information
Book Title: Extracellular Matrix in Development
Editors: Douglas W. DeSimone, Robert P. Mecham
Series Title: Biology of Extracellular Matrix
DOI: https://doi.org/10.1007/978-3-642-35935-4
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2013
Hardcover ISBN: 978-3-642-35934-7Published: 29 March 2013
Softcover ISBN: 978-3-642-42740-4Published: 09 April 2015
eBook ISBN: 978-3-642-35935-4Published: 15 March 2013
Series ISSN: 0887-3224
Series E-ISSN: 2191-1959
Edition Number: 1
Number of Pages: X, 253
Topics: Developmental Biology, Cell Biology, Regenerative Medicine/Tissue Engineering, Cytokines and Growth Factors, Stem Cells