Overview
First methods book which includes many detailed descriptions
Absolutely needed and thus timely for the scientific community
Comprises 15% more content and includes the special features mentioned
Includes supplementary material: sn.pub/extras
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Table of contents (14 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Protein Folding Kinetics - Biophysical Methods (2nd Edition) gives a deep insight into the principles and concepts of the kinetic and structural resolution of fast chemical and biophysical reactions of proteins with emphasis on protein-folding reactions. The study of fast protein-folding reactions and the understanding of the folding paradox have significantly advanced due to the recent development of new biophysical methods which allow not only kinetic resolution in the sub-millisecond time scale but also structural resolution with unprecedented precision. Pathways and structures of early and late folding events and the transition state structures of fast- and ultrafast-folding proteins can now be studied in far more detail. Important techniques include biophysical, chemical, molecular biological and mathematical methods, in particular protein engineering, Phi-value analysis, time-resolved circular dichroism, optical triggers and pulsed infrared LASER methods, pressure and temperature jump, ultrafast mixing, stopped flow and quenched flow, dielectric relaxation and electric-field-jump, acoustic relaxation, fluorescence- and isotope-labeling, H/D exchange methods, NMR line broadening and stopped-flow NMR, transition state theory, solutions of rate equations, and evolutionary computer programming. Protein Folding Kinetics - Biophysical Methods is written for students and researchers in biochemistry, biophysics, and related fields.
Special features in the second edition:
-Includes detailed information and 12 color figures on the high resolution of folding transition states.
-Discusses structural determinants of the rate of protein folding on a timescale from microseconds to seconds.
-Provides information on self-evolving computer programs for protein-folding simulations and protein-structure predictions.
Authors and Affiliations
Bibliographic Information
Book Title: Protein Folding Kinetics
Book Subtitle: Biophysical Methods
Authors: Bengt Nölting
DOI: https://doi.org/10.1007/b138868
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2006
Hardcover ISBN: 978-3-540-27277-9Published: 24 August 2005
Softcover ISBN: 978-3-642-06604-7Published: 12 February 2010
eBook ISBN: 978-3-540-27278-6Published: 28 November 2005
Edition Number: 2
Number of Pages: XVI, 222
Number of Illustrations: 158 b/w illustrations, 12 illustrations in colour
Topics: Protein Science, Biochemistry, general, Biological and Medical Physics, Biophysics, Biotechnology, Food Science