Uterus Transplantation

1. Front Matter

   Pages i-xi

   PDF

2. Introduction: Uterus Transplantation

   • Mats Brännström

   Pages 1-10

3. The Ethics of Uterus Transplantation: Moral Challenges and Recommendations for Progress

   • Arthur L. Caplan, Brendan Parent, Pasquale Patrizio

   Pages 11-23

4. Patients with Uterine Factor Infertility: General

   • Cesar Diaz Garcia

   Pages 25-32

5. MRKH Patients and Their Preparations for Uterus Transplantation

   • Dorit Schöller, Sara Brucker

   Pages 33-37

6. Rodent Animal Research in UTx

   • Randa Akouri, Min Jong Song, Cesar Diaz Garcia

   Pages 39-50

7. Domestic Species Research in Uterus Transplantation

   • Mats Brännström

   Pages 51-55

8. Nonhuman Primate Research in Uterus Transplantation

   • Iori Kisu, Yusuke Matoba, Kouji Banno, Daisuke Aoki

   Pages 57-67

9. Human Preclinical Research in Uterus Transplantation

   • Mats Brännström

   Pages 69-72

10. Medical Work-Up of the Recipient

    • Jana Pittman, Rebecca Deans, Mats Brännström

    Pages 73-78

11. Live or Deceased Uterus Donor

    • Michael Olausson

    Pages 79-82

12. Medical Work-Up of the Live Donor

    • Mats Brännström, Pernilla Dahm-Kähler

    Pages 83-87

13. Medical Work-Up of the Deceased Donor

    • Anne C. Davis, Rebecca Flyckt, Tommaso Falcone

    Pages 89-93

14. Psychological Evaluations Before Uterus Transplantation

    • Stina Järvholm

    Pages 95-101

15. Assisted Reproduction Before and After Uterus Transplantation

    • Lars B. Nilsson, Jan I. Olofsson

    Pages 103-110

16. Surgical Technique of Live Donor in Uterus Transplantation

    • Mats Brännström, Pernilla Dahm-Kähler

    Pages 111-117

17. Surgical Technique of Deceased Donor in Uterus Transplantation

    • Andreas Tzakis, Michael Olausson, Tommaso Falcone

    Pages 119-127

18. Surgical Technique in Preparation of Recipient

    • Janusz Marcickiewicz, Mats Brännström

    Pages 129-133

19. Back-Table Preparation and Flushing of the Uterus

    • Niclas Kvarnström, Mats Brännström

    Pages 135-138

20. Surgical Technique for Vascular Anastomosis of the Uterine Graft

    • Michael Olausson, Niclas Kvarnström

    Pages 139-145

This book discusses all aspects of the uterus transplantation procedure in women who are childless because of a dysfunctional or missing uterus, from initial pre-operative investigations to follow-up after the uterine graft has been removed. All the international experts who are engaged in clinical activities and/or research in this field have contributed one or more of the book’s chapters.

Since the first live birth following uterus transplantation was reported in Sweden in September 2014, the field has been rapidly evolving around the globe: the first cases in USA, Germany, China, Brazil, and Czech Republic were performed in 2016 and several other centres are preparing for clinical trials of uterus transplantation.

Uterus transplantation is a subject that attracts the attention of many bioethicists, and like all other major procedures in transplantation surgery and assisted reproduction techniques, it is a complex process that requires a multidisciplinary team if it is to be successful. As such the book is a valuable resource not only for clinicians from many disciplines, but also for nurses, ethicists, psychologists and researchers. 

• Infertility
• Immunosuppression
• Assisted reproductive technologies
• Donors
• Surgical technique

• University of Gothenburg, Gothenburg, Sweden

  Mats Brännström

Mats Brännström is a professor at the University of Gothenburg and chairman of the Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden. His main goal is to improve diagnostics, treatment and postoperative care for a number of common female health issues by performing experimental, clinical and epidemiological studies. He is the first clinician to have performed successful uterus transplantation in women who are childless because of a dysfunctional or missing uterus. Prof. Brannstrom is a member of numerous medical societies, and has won several awards. 

Policies and ethics