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Self-Assembled Molecules – New Kind of Protein Ligands

Supramolecular Ligands

Herausgeber: Roterman, Irena, Konieczny, Leszek (Eds.)

  • An up-to-date account of supramolecular ligands
  • Essential reading for academic and industrial scientists interested in drug targeting
  • A comprehensive overview of the enhancement of immune complexation
Weitere Vorteile

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  • ISBN 978-3-319-65639-7
  • Dieses Buch ist ein Open Access Buch und ist frei zugänglich auf link.springer.com
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Softcover 53,49 €
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Über dieses Buch

The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. This book is an open access under a CC BY license. 

Über die Autor*innen

Dr Irena Roterman-Konieczna – professor of bioinformatics  heads the bioinformatics group at the Jagiellonian University – Medical College and the Faculty of Physics, Astronomy and Applied Computer Science, Poland. Her background is the theoretical chemistry and her research focuses on bioinformatics with a special focus on protein structure prediction. Involved also in education of medical students and students of computer science developing different forms of simulations in medicine.

Inhaltsverzeichnis (8 Kapitel)

Inhaltsverzeichnis (8 Kapitel)
  • Supramolecular Systems as Protein Ligands

    Seiten 1-20

    Rybarska, Joanna (et al.)

  • Supramolecular Congo Red as Specific Ligand of Antibodies Engaged in Immune Complex

    Seiten 21-41

    Jagusiak, Anna (et al.)

  • Protein Conditioning for Binding Congo Red and Other Supramolecular Ligands

    Seiten 43-60

    Zemanek, Grzegorz (et al.)

  • Metal Ions Introduced to Proteins by Supramolecular Ligands

    Seiten 61-76

    Woźnicka, Olga (et al.)

  • Possible Mechanism of Amyloidogenesis of V Domains

    Seiten 77-100

    Banach, Mateusz (et al.)

Dieses Buch kaufen

eBook  
  • ISBN 978-3-319-65639-7
  • Dieses Buch ist ein Open Access Buch und ist frei zugänglich auf link.springer.com
Hardcover 53,49 €
Preis für Deutschland (Brutto)
Softcover 53,49 €
Preis für Deutschland (Brutto)
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Bibliografische Information

Bibliographic Information
Buchtitel
Self-Assembled Molecules – New Kind of Protein Ligands
Buchuntertitel
Supramolecular Ligands
Herausgeber
  • Irena Roterman
  • Leszek Konieczny
Copyright
2018
Verlag
Springer International Publishing
Copyright Inhaber
The Editor(s) (if applicable) and The Author(s)
eBook ISBN
978-3-319-65639-7
DOI
10.1007/978-3-319-65639-7
Hardcover ISBN
978-3-319-65638-0
Softcover ISBN
978-3-319-88071-6
Auflage
1
Seitenzahl
XII, 136
Anzahl der Bilder
54 schwarz-weiß Abbildungen, 44 Abbildungen in Farbe
Themen