Overview
- Covers all aspects of apoptosis
- Chapters submitted from world renowned researchers
- Unique in defining the relationship between the regulatory mechanisms
Part of the book series: Advances in Biochemistry in Health and Disease (ABHD, volume 18)
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Table of contents (15 chapters)
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Front Matter
Keywords
About this book
While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death ismerely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event.
Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway.
The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.
Editors and Affiliations
Bibliographic Information
Book Title: Biochemistry of Apoptosis and Autophagy
Editors: Lorrie A. Kirshenbaum
Series Title: Advances in Biochemistry in Health and Disease
DOI: https://doi.org/10.1007/978-3-030-78799-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-78798-1Published: 30 November 2021
Softcover ISBN: 978-3-030-78801-8Published: 30 November 2022
eBook ISBN: 978-3-030-78799-8Published: 29 November 2021
Series ISSN: 2512-2142
Series E-ISSN: 2512-2150
Edition Number: 1
Number of Pages: XVI, 283
Number of Illustrations: 8 b/w illustrations, 27 illustrations in colour
Topics: Cell Biology