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Astrocytes in Psychiatric Disorders

  • Book
  • © 2021

Overview

Editors:
  1. Baoman Li

    1. Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, China

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  2. Vladimir Parpura

    1. Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, USA

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  3. Alexei Verkhratsky

    1. Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

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  4. Caterina Scuderi

    1. Department of Physiology and Pharmacology “Vittorio Erspamer”, Sapienza University of Rome, Rome, Italy

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  • Serves as a comprehensive volume outlining the role of astrocytes in psychiatric disorders
  • Provides discussions of astroglia in mood disorders, schizophrenia, addictive disorders and eating disorders
  • Explores ways in targeting astrocytes in the therapeutic management of neuropsychaitric disorders

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 26)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-vi
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  2. General Aspects of Astrogliopathology with Emphasis on Neurocognitive Disorders

    1. Front Matter

      Pages 1-1
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    2. Neuroglia in Psychiatric Disorders

      • Caterina Scuderi, Alexei Verkhratsky, Vladimir Parpura, Baoman Li
      Pages 3-19

    3. Astrocytes: The Housekeepers and Guardians of the CNS

      • Alexei Verkhratsky, Vladimir Parpura, Baoman Li, Caterina Scuderi
      Pages 21-53

    4. Principles of Astrogliopathology

      • Alexei Verkhratsky, Baoman Li, Caterina Scuderi, Vladimir Parpura
      Pages 55-73

    5. Morphological Features of Astrocytes in Health and Neuropsychiatric Disorders

      • Celia Roman, Eugenia Vivi, Barbara Di Benedetto
      Pages 75-92

  3. Astroglia in Mood Disorders

    1. Front Matter

      Pages 93-93
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    2. Astrocytes in Bipolar Disorder

      • Arthur M. Butt, Andrea D. Rivera
      Pages 95-113

    3. Astroglia Abnormalities in Post-stroke Mood Disorders

      • Tracey Singer, Sarah Ding, Shinghua Ding
      Pages 115-138

    4. Astroglia and Obsessive Compulsive Disorder

      • Kohichi Tanaka
      Pages 139-149

  4. Astroglia in Schizophrenia

    1. Front Matter

      Pages 151-151
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    2. Astrocytes in Neuropsychiatric Disorders: A Review of Postmortem Evidence

      • Xiaolu Zhang, Rawan S. Alnafisah, Abdul-Rizaq A. Hamoud, Rammohan Shukla, Robert E. McCullumsmith, Sinead M. O’Donovan
      Pages 153-172

    3. Astrocyte Bioenergetics and Major Psychiatric Disorders

      • Ivan V. Maly, Michael J. Morales, Mikhail V. Pletnikov
      Pages 173-227

  5. Astroglia in Addictive Disorders

    1. Front Matter

      Pages 229-229
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    2. Astrocytes in Addictive Disorders

      • Anna Kruyer, Michael D. Scofield
      Pages 231-254

    3. Astroglia in the Vulnerability and Maintenance of Alcohol Use Disorders

      • José Javier Miguel-Hidalgo
      Pages 255-279

  6. Astroglia in Eating Disorders

    1. Front Matter

      Pages 281-281
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    2. Brain Volume Loss, Astrocyte Reduction, and Inflammation in Anorexia Nervosa

      • Jochen Seitz, Stefanie Trinh, Vanessa Kogel, Cordian Beyer
      Pages 283-313

  7. Targeting Astrocytes in Therapeutic Management of Neuropsychiatric Disorders

    1. Front Matter

      Pages 315-315
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    2. Astroglial Serotonin Receptors as the Central Target of Classic Antidepressants

      • Alexei Verkhratsky, Vladimir Parpura, Caterina Scuderi, Baoman Li
      Pages 317-347
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Keywords

About this book

This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders.  Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.

Editors and Affiliations

  • Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, China

    Baoman Li

  • Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, USA

    Vladimir Parpura

  • Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

    Alexei Verkhratsky

  • Department of Physiology and Pharmacology “Vittorio Erspamer”, Sapienza University of Rome, Rome, Italy

    Caterina Scuderi

About the editors

Vladimir Parpura is a Professor in the Department of Neurobiology at The University of Alabama in Birmingham, Alabama. 

Alexei Verkhratsky is a Professor of Neurophysiology in the Faculty of Life Sciences at The University of Manchester in Manchester, United Kingdom. 

Caterina Scuderi is an Assistant Professor in the Department of Physiology and Pharmacology at Sapienza University of Rome. 

Baoman Li is a  Professor at the Laboratory Teaching Center at the School of Forensic Medicine, China Medical University in Shenyang, China. 

Bibliographic Information

  • Book Title: Astrocytes in Psychiatric Disorders

  • Editors: Baoman Li, Vladimir Parpura, Alexei Verkhratsky, Caterina Scuderi

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-3-030-77375-5

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-77374-8Published: 10 December 2021

  • Softcover ISBN: 978-3-030-77377-9Published: 11 December 2022

  • eBook ISBN: 978-3-030-77375-5Published: 09 December 2021

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: VI, 377

  • Number of Illustrations: 36 b/w illustrations

  • Topics: Neurosciences, Neurology, Physiology, Neuropsychology

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