Coronavirus Disease - COVID-19

1. Front Matter

   Pages i-xx

   PDF

2. Introduction on Coronavirus Disease (COVID-19) Pandemic: The Global Challenge

   • Nima Rezaei, Saboura Ashkevarian, Mahsa Keshavarz Fathi, Sara Hanaei, Zahra Kolahchi, Seyedeh-Sanam Ladi Seyedian et al.

   Pages 1-22

3. Coronaviruses: What Should We Know About the Characteristics of Viruses?

   • Wei Ji

   Pages 23-39

4. Ecology and Evolution of Betacoronaviruses

   • Eduardo Rodríguez-Román, Adrian J. Gibbs

   Pages 41-60

5. The Epidemiologic Aspects of COVID-19 Outbreak: Spreading Beyond Expectations

   • Sara Hanaei, Farnam Mohebi, Maziar Moradi-Lakeh, Parnian Jabbari, Surinder Kumar Mehta, Liudmyla S. Kryvenko et al.

   Pages 61-79

6. The Incubation Period of COVID-19: Current Understanding and Modeling Technique

   • Char Leung

   Pages 81-90

7. Coronavirus: Pure Infectious Disease or Genetic Predisposition

   • Farzaneh Darbeheshti, Hassan Abolhassani, Mohammad Bashashati, Saeid Ghavami, Sepideh Shahkarami, Samaneh Zoghi et al.

   Pages 91-107

8. Genetic Polymorphisms in the Host and COVID-19 Infection

   • Joris R. Delanghe, Marc L. De Buyzere, Marijn M. Speeckaert

   Pages 109-118

9. How COVID-19 Has Globalized: Unknown Origin, Rapid Transmission, and the Immune System Nourishment

   • Amene Saghazadeh, Nima Rezaei

   Pages 119-147

10. Potential Antiviral Immune Response Against COVID-19: Lessons Learned from SARS-CoV

    • Mahzad Akbarpour, Laleh Sharifi, Amir Reza Safdarian, Pooya Farhangnia, Mahdis Borjkhani, Nima Rezaei

    Pages 149-167

11. COVID-19 and Cell Stress

    • Abdo A. Elfiky, Ibrahim M. Ibrahim, Fatma G. Amin, Alaa M. Ismail, Wael M. Elshemey

    Pages 169-178

12. Clinical Manifestations of COVID-19

    • Mahsa Eskian, Nima Rezaei

    Pages 179-196

13. Pediatrics and COVID-19

    • Tuna Toptan, Sandra Ciesek, Sebastian Hoehl

    Pages 197-208

14. Geriatrics and COVID-19

    • Mona Mirbeyk, Amene Saghazadeh, Nima Rezaei

    Pages 209-222

15. Coronavirus Diseases in Pregnant Women, the Placenta, Fetus, and Neonate

    • David A. Schwartz, Amareen Dhaliwal

    Pages 223-241

16. COVID-19 in Patients with Hypertension

    • Thiago Quinaglia, Mahsima Shabani, Nima Rezaei

    Pages 243-261

17. COVID-19 and Cardiovascular Diseases

    • Babak Geraiely, Niloufar Samiei, Parham Sadeghipour, Azita H. Talasaz, Seyedeh Hamideh Mortazavi, Roya Sattarzadeh Badkoubeh

    Pages 263-291

18. How Prevalent Is Cancer in Confirmed Cases with Coronaviruses and Severe Acute Respiratory Syndromes?

    • Maryam Fotouhi, Elham Samami, Sahar Mohseni, Amir Nasrollahizadeh, Mohammad Haddadi, Mona Mirbeyk et al.

    Pages 293-313

19. COVID-19 in Patients with Cancer

    • Ali Nowroozi, Sepideh Razi, Kamal Kant Sahu, Fabio Grizzi, Jann Arends, Mahsa Keshavarz-Fathi et al.

    Pages 315-331

20. COVID-19 and Tropical Infection: Complexity and Concurrence

    • Pathum Sookaromdee, Viroj Wiwanitkit

    Pages 333-341

In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and  vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19).

• 2019-nCoV
• Acute respiratory disease
• Infection
• Immune system
• MERS
• SARS

• Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

  Nima Rezaei

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital.  Professor Rezaei is now the Full Professor of Immunology and Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Deputy President of the Research Center for Immunodeficiencies. He is also the founding President of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than 50 research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is an editorial assistant or board member for more than 30 international journals. He hasedited more than 30 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 800 articles in the international scientific journals.

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