Overview
- Most comprehensive work on sterol signaling
- Highlights novel discoveries in oxysterol and bile acid functioning
- Explains sterol biosynthesis as well as their role in disease
- With contributions of well-known specialists and experts in the field
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Table of contents (7 chapters)
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Front Matter
Keywords
About this book
This book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease. It offers insight into new research findings, focusing specifically on novel discoveries in bile acid and oxysterol signaling, including the lanosterol-to-cholesterol intermediates. Special attention is paid on the sex distribution of these sterols (male or female) and their sexually dimorphic roles in mammalian species, such as human, rat and mouse. Since sterols and drugs (xenobiotics) use many identical receptor-mediated signaling pathways, the book will be interesting for researchers working on the cross-road of endogenous and xenobiotic metabolism, it is intended for advanced students and scientists in molecular biology and biochemistry as well as for medical doctors in hepatology.
Editors and Affiliations
About the editors
Damjana Rozman is full Professor of Biochemistry and Molecular Biology at the Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia and Head of the Centre for Functional Genomcis and Bio-Chips (CFGBC).
Rolf Gebhardt is Professor (em.) of Biochemistry at the Rudolf Schönheimer Institute of Biochemistry, Department of General Biochemistry, University of Leipzig, Faculty of Medicine, Leipzig, Germany.
Bibliographic Information
Book Title: Mammalian Sterols
Book Subtitle: Novel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids
Editors: Damjana Rozman, Rolf Gebhardt
DOI: https://doi.org/10.1007/978-3-030-39684-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-39683-1Published: 11 August 2020
Softcover ISBN: 978-3-030-39686-2Published: 12 August 2021
eBook ISBN: 978-3-030-39684-8Published: 10 August 2020
Edition Number: 1
Number of Pages: V, 171
Number of Illustrations: 43 b/w illustrations, 14 illustrations in colour
Topics: Molecular Medicine, Animal Biochemistry, Hepatology, Lipidology, Metabolomics, Human Genetics