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Advances in Experimental Medicine and Biology

Notch Signaling in Embryology and Cancer

Molecular Biology of Notch Signaling

Herausgeber: Reichrath, Jörg, Reichrath, Sandra (Eds.)

Vorschau
  • The content is presented in a logical and coherent structure, enabling the reader to readily access relevant information
  • The volume editors are renowned experts on Notch and Notch Signaling and the chapter contributors are all internationally-recognized researchers
  • Timely and urgently needed update in a rapidly moving field
Weitere Vorteile

Dieses Buch kaufen

eBook 117,69 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-36422-9
  • Versehen mit digitalem Wasserzeichen, DRM-frei
  • Erhältliche Formate: PDF, EPUB
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  • Sofortiger eBook Download nach Kauf
Hardcover 160,49 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-36421-2
  • Kostenfreier Versand für Individualkunden weltweit
  • Gewöhnlich versandfertig in 3-5 Werktagen.
Über dieses Buch

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. 

Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors.  Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.

Über den Autor

Sandra and Jörg Reichrath are working at the Clinic for Dermatology; Allergology and Venerology of the Saarland University Hospital in Homburg/Saar. Germany. Main research interests include photobiology, carcinogenesis of skin cancer (with a special interest for the role of ultraviolet radiation, Notch and p53), and the relevance of the vitamin D endocrine system for health and disease. Sandra received her academic degrees (Dipl. Biol. and Dr. rer. nat.) from the Albert-Ludwigs-Universität (Freiburg, Germany) and from Saarland University (Saarbrücken/Homburg, Germany), respectively. Jörg received his academic degrees (Dr. med., venia legendi) from Saarland University (Saarbrücken/Homburg, Germany). He has been awarded numerous prizes including the Arnold-Rikli-Prize in 2006.

Inhaltsverzeichnis (10 Kapitel)

Inhaltsverzeichnis (10 Kapitel)

Dieses Buch kaufen

eBook 117,69 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-36422-9
  • Versehen mit digitalem Wasserzeichen, DRM-frei
  • Erhältliche Formate: PDF, EPUB
  • eBooks sind auf allen Endgeräten nutzbar
  • Sofortiger eBook Download nach Kauf
Hardcover 160,49 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-36421-2
  • Kostenfreier Versand für Individualkunden weltweit
  • Gewöhnlich versandfertig in 3-5 Werktagen.
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Bibliografische Information

Bibliographic Information
Buchtitel
Notch Signaling in Embryology and Cancer
Buchuntertitel
Molecular Biology of Notch Signaling
Herausgeber
  • Jörg Reichrath
  • Sandra Reichrath
Titel der Buchreihe
Advances in Experimental Medicine and Biology
Buchreihen Band
1227
Copyright
2020
Verlag
Springer International Publishing
Copyright Inhaber
Springer Nature Switzerland AG
eBook ISBN
978-3-030-36422-9
DOI
10.1007/978-3-030-36422-9
Hardcover ISBN
978-3-030-36421-2
Buchreihen ISSN
0065-2598
Auflage
2
Seitenzahl
XIII, 172
Anzahl der Bilder
1 schwarz-weiß Abbildungen, 31 Abbildungen in Farbe
Themen