Principles of Cancer Treatment and Anticancer Drug Development

Autoren: Link, Wolfgang

Vorschau
  • Explains in easy-to-understand language, how current medicines against cancer work and how we find new ones for interested readers and students
  • It includes the most updated options to treat cancer and provides a unique insight into the world of modern drug discovery
  • Provides a unique way for teachers and students to teach/learn about basic concepts in biomedical and drug research with simple and comprehensive figures and tables, text boxes.
Weitere Vorteile

Dieses Buch kaufen

eBook 42,79 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-18722-4
  • Versehen mit digitalem Wasserzeichen, DRM-frei
  • Erhältliche Formate: EPUB, PDF
  • eBooks sind auf allen Endgeräten nutzbar
  • Sofortiger eBook Download nach Kauf
Hardcover 53,49 €
Preis für Deutschland (Brutto)
Softcover 53,49 €
Preis für Deutschland (Brutto)
Über dieses Lehrbuch

This book explains how current medicines against cancer work and how we find new ones. It provides an easy-to-understand overview of current options to treat patients with cancer, which includes Surgery, Radiation therapy, Chemotherapy, Targeted therapy and Immunotherapy. The efficiency of all these treatments is limited by the capacity of cancer cells to escape therapy. This book explains the mechanisms of anti-cancer drug resistance and strategies to overcome it. The discovery and development process of a new drug is detailed beginning with the identification and validation of a therapeutic target, the identification of an inhibitor of the target and its subsequent preclinical and clinical development until its approval by regulatory authorities. Particular emphasis has been given to specific aspects of the development process including lead generation and optimization, pharmacokinetics, ADME analysis, pharmacodynamics, toxicity and efficacy assessment, investigational new drug (IND) and new drug application (NDA) and the design of clinical trial and their phases. The book covers many aspects of modern personalized oncology and discusses economic aspects of our current system of developing new medicines and its impact on our societies and on future drug research.

The author of this book, Dr. Link counts with more than 20 years of experience in biomedical research reflected in numerous publications, patents and key note and plenary presentations at international conferences. Interested readers, students and teachers should read this book as it provides a unique way to learn/teach about basic concepts in oncology and anti-cancer drug research.

Über die Autor*innen

Dr. Wolfgang Link is an Assistant Professor at the Universisty of Algarve in the Department of Biomedical Sciences and Medicine. He is also Head of Oncobiology at the Center for Biomedical Research (CBMR).

Stimmen zum Buch

“‘Principles of Cancer Treatment and Anticancer Drug Development’ provides a welcome introduction to the treatment of cancer and the development of new cancer therapies. Every clinical researcher would benefit from a basic understanding of the treatment and research context of cancer clinical research studies.” (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 16 (2), February, 2020)

Inhaltsverzeichnis (5 Kapitel)

Inhaltsverzeichnis (5 Kapitel)

Dieses Buch kaufen

eBook 42,79 €
Preis für Deutschland (Brutto)
  • ISBN 978-3-030-18722-4
  • Versehen mit digitalem Wasserzeichen, DRM-frei
  • Erhältliche Formate: EPUB, PDF
  • eBooks sind auf allen Endgeräten nutzbar
  • Sofortiger eBook Download nach Kauf
Hardcover 53,49 €
Preis für Deutschland (Brutto)
Softcover 53,49 €
Preis für Deutschland (Brutto)
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Bibliografische Information

Bibliographic Information
Buchtitel
Principles of Cancer Treatment and Anticancer Drug Development
Autoren
Copyright
2019
Verlag
Springer International Publishing
Copyright Inhaber
Springer Nature Switzerland AG
Vertriebsrechte
The target group are any students following master courses in Biomedical Sciences and Advanced graduate (Bachelor) in a wide range of Health Sciences programs
eBook ISBN
978-3-030-18722-4
DOI
10.1007/978-3-030-18722-4
Hardcover ISBN
978-3-030-18721-7
Softcover ISBN
978-3-030-18724-8
Auflage
1
Seitenzahl
XIV, 145
Anzahl der Bilder
2 schwarz-weiß Abbildungen, 43 Abbildungen in Farbe
Themen