HDAC/HAT Function Assessment and Inhibitor Development
Methods and Protocols
Herausgeber: Krämer, Oliver H. (Ed.)
Vorschau- Includes cutting-edge methods and protocols to study HDACs and HATs
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
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This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro. The book also covers the generation and specificity of deacetylase inhibitors and how such agents can be used to test experimental hypotheses. Written for the popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Comprehensive and practical, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols serves as an ideal guide to this vital area of study.
- Inhaltsverzeichnis (31 Kapitel)
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Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells
Seiten 3-10
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Assessment of HDACi-Induced Protein Cleavage by Caspases
Seiten 11-22
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Assessment of HDACi-Induced Cytotoxicity
Seiten 23-45
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Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization
Seiten 47-59
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Analysis of Histone Deacetylase-Dependent Effects on Cell Migration Using the Stripe Assay
Seiten 61-75
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Inhaltsverzeichnis (31 Kapitel)
- Download Vorwort 1 PDF (21.2 KB)
- Download Probeseiten 1 PDF (605.7 KB)
- Download Inhaltsverzeichnis PDF (43.7 KB)
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Bibliografische Information
- Bibliographic Information
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- Buchtitel
- HDAC/HAT Function Assessment and Inhibitor Development
- Buchuntertitel
- Methods and Protocols
- Herausgeber
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- Oliver H. Krämer
- Titel der Buchreihe
- Methods in Molecular Biology
- Buchreihen Band
- 1510
- Copyright
- 2017
- Verlag
- Humana Press
- Copyright Inhaber
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4939-6527-4
- DOI
- 10.1007/978-1-4939-6527-4
- Hardcover ISBN
- 978-1-4939-6525-0
- Softcover ISBN
- 978-1-4939-8226-4
- Buchreihen ISSN
- 1064-3745
- Auflage
- 1
- Seitenzahl
- XIV, 415
- Anzahl der Bilder
- 39 schwarz-weiß Abbildungen, 58 Abbildungen in Farbe
- Themen
