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Computer-Aided Tissue Engineering

Methods and Protocols

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2147)

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Table of contents (15 protocols)

  1. Front Matter

    Pages i-xi
  2. Design Principles

    1. Front Matter

      Pages 1-1
    2. Biomimetic Boundary-Based Scaffold Design for Tissue Engineering Applications

      • Henrique A. Almeida, Paulo J. Bártolo
      Pages 3-18
    3. 3D Printing of Functionally Graded Films by Controlling Process Parameters

      • Alessandra Bonfanti, Loris Domenicale, Atul Bhaskar
      Pages 31-42
  3. Biomaterials for Computer-Aided Tissue Engineering

    1. Front Matter

      Pages 43-43
    2. Photocurable Biopolymers for Coaxial Bioprinting

      • Marco Costantini, Andrea Barbetta, Wojciech Swieszkowski, Dror Seliktar, Cesare Gargioli, Alberto Rainer
      Pages 45-54
    3. Synthesis of an UV-Curable Divinyl-Fumarate Poly-ε-Caprolactone for Stereolithography Applications

      • Alfredo Ronca, Sara Ronca, Giuseppe Forte, Luigi Ambrosio
      Pages 55-62
    4. Nanocomposite Clay-Based Bioinks for Skeletal Tissue Engineering

      • Gianluca Cidonio, Michael Glinka, Yang-Hee Kim, Jonathan I. Dawson, Richard O. C. Oreffo
      Pages 63-72
  4. Technological Platforms and Manufacturing Processes

    1. Front Matter

      Pages 73-73
    2. Additive Manufacturing Using Melt Extruded Thermoplastics for Tissue Engineering

      • Andrea Roberto Calore, Ravi Sinha, Jules Harings, Katrien V. Bernaerts, Carlos Mota, Lorenzo Moroni
      Pages 75-99
    3. Computer-Aided Wet-Spinning

      • Dario Puppi, Federica Chiellini
      Pages 101-110
    4. Production of Scaffolds Using Melt Electrospinning Writing and Cell Seeding

      • Eleonore C. L. Bolle, Deanna Nicdao, Paul D. Dalton, Tim R. Dargaville
      Pages 111-124
    5. Direct-Write Deposition of Thermogels

      • Sara Maria Giannitelli, Valeria Chiono, Pamela Mozetic
      Pages 137-142
    6. 3D Bioprinting of Complex, Cell-laden Alginate Constructs

      • Atabak Ghanizadeh Tabriz, Dirk-Jan Cornelissen, Wenmiao Shu
      Pages 143-148
    7. Surface Tension-Assisted Additive Manufacturing of Tubular, Multicomponent Biomaterials

      • Elia A. Guzzi, Héloïse Ragelle, Mark W. Tibbitt
      Pages 149-160
  5. Applicative Scenarios

    1. Front Matter

      Pages 161-161
    2. Bioprinting of Complex Vascularized Tissues

      • Wei Zhu, Claire Yu, Bingjie Sun, Shaochen Chen
      Pages 163-173
    3. A Scaffold Free 3D Bioprinted Cartilage Model for In Vitro Toxicology

      • Pallab Datta, Yang Wu, Yin Yu, Kazim K. Moncal, Ibrahim T. Ozbolat
      Pages 175-183

About this book

This volume details protocols encompassing different aspects of computer aided design and manufacturing of 3D scaffolds and biofabricated constructs for tissue engineering applications. Chapters are divided into four parts covering optimization of scaffold architectures for computer aided tissue engineering, synthetic routes to biomaterials compatible, technological platforms and manufacturing processes, and relevant applicative scenarios. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Computer-Aided Tissue Engineering: Methods and Protocols aims to be useful for new and experienced laboratory researchers working on different aspects of corneal regeneration.

Editors and Affiliations

  • Università Campus Bio-Medico di Roma, Rome, Italy

    Alberto Rainer

  • Department of Complex Tissue Regeneration, MERLN Institute for Technology Inspired Regenerative Medicine, Maastricht, The Netherlands

    Lorenzo Moroni

Bibliographic Information

  • Book Title: Computer-Aided Tissue Engineering

  • Book Subtitle: Methods and Protocols

  • Editors: Alberto Rainer, Lorenzo Moroni

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-0716-0611-7

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2021

  • Hardcover ISBN: 978-1-0716-0610-0Published: 26 August 2020

  • Softcover ISBN: 978-1-0716-0613-1Published: 26 August 2021

  • eBook ISBN: 978-1-0716-0611-7Published: 25 August 2020

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 188

  • Number of Illustrations: 7 b/w illustrations, 61 illustrations in colour

  • Topics: Biotechnology, Regenerative Medicine/Tissue Engineering

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access