New Developments and New Applications in Animal Cell Technology

Genetic Manipulation of the Mammalian Genome

• R. Jaenisch

Engineering Glycosylation in Animal Cells

• J. E. Bailey, E. Prati, J. Jean-Mairet, A. Sburlati, P. Umaña

Sessions on: Biosynthesis and Post-Translational Modifications of Recombinant Proteins, and Cell Physiology and Metabolic Engineering of Animal Cells

• B. Griffiths, J. Lupker, M. Al-Rubeai, J.E. Bailey

Front Matter

Enhanced Recombinant Protein Expression in Insect Cells in the Presence of Dimethylsulfoxide (DMSO)

• Luciano. Kamos, James F. Kane, Amy A. Murnane

Studies of the Hepatitis C Virus Recombinant Protein Production and Its Effects on SF-9 Insect Cells Metabolism

• Céline M. Charon

The Human Multidrug Transporter (MDR1) Expressed in the Baculovirus-SF9 Insect Cell System

• K. Szabó, E. Bakos, E. Welker, A. Varadi, H. R. Goodfellow, C. F. Higgins et al.

Glutamine Synthetase Transfected Cells May Avoid Selection by Releasing Glutamine

• P. Bird, E. Bolam, L. Castell, O. Obeid, N. Darton, G. Hale

Study of Different Cell Culture Conditions for the Production of a “Reshaped” Mab in NSO Cells

• A. J. Castillo, A. Fernandez, T. Boggiano, P. Pugeaud, I. W. Marison

Increasing Monoclonal Antibody Productivity by Semicontinuous Substitution of Production Medium for Growth Medium

• F. Franěk, K. Šrámková

Expression of Recombinant Human Insulin in Chinese Hamster Ovary Cells is Complicated by Intracellular Insulin-Degrading Enzymes

• S. C. O. Pak, S. M. N. Hunt, M. J. Sleigh, P. P. Gray

High Yield Expression of Recombinant Plasma Factors: Use of Recombinant Endoprotease Derivatives In Vivo and In Vitro

• U. Schlokat, A. Preininger, M. Himmelspach, G. Mohr, B. Fischer, F. Dorner

The Role of Cell Cycle in Determining Levels of Gene Expression in Cho Cells

• D. R. Lloyd, V. Leelavatcharamas, D. C. Edwards, A. N. Emery, M. Al-ubeai

Heterogeneity within DHFR-Mediated Gene Amplified Population of Cho Cells Producting Chimeric Antibodies

• No Soo Kim, Sang Jick Kim, Gyun Min Lee

Immunofluorescence Detection of Recombinant Monoclonal Antibody as a Tool in the Characterization of Chinese Hamster Ovary Cell Lines

• Cheryl Ann S. Kinney, Robin E. Trala, Linda C. Hendricks, Timothy D. Hill

Electrolyzed Reduced Water Which Can Scavenge Active Oxygen Species Supresses Cell Growth and Regulates Gene Expression of Animal Cells

• S. Shirahata, S. Kabayama, K. Kusumoto, M. Gotoh, K. Teruya, K. Otsubo et al.

Differential Gene Expression of Cytochrome P450 in Immortalised Hepatocyte Cell Lines

• H. T. Kelly, K. Anderson, E. Hill, H. Grant, C. MacDonald

Post-Transcriptional Control of Recombinant Gene Expression: mRNA Retargeting and Regulation of Expression

• K. A. Partridge, A. Johannessen, A. Tauler, I. F. Pryme, J. E. Hesketh

Transient Transfection in Mammalian Cells

• E. -J. Schlaeger, J. Y. Legendre, A. Trzeciak, E. A. Kitas, K. Christensen, U. Deuschle et al.