Overview
- Gives a holistic overview of efforts made by various research disciplines to combat the MDR problem through natural products
- Introduces new dimensions in antibacterial drug discovery and alternative modes of combating bacterial infections
- Suggests ways for minimizing the emergence and spread of MDR pathogens
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Table of contents (28 chapters)
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Front Matter
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The Challenge of Antibiotic Resistance and Tolerance
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Front Matter
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New Antibiotic Drug Discovery Approaches and Progress
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Front Matter
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Keywords
About this book
This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.
Editors and Affiliations
About the editors
Professor Iqbal Ahmad
Iqbal Ahmad is a Full Professor and former Chair of the Department of Agricultural Microbiology, Aligarh Muslim University, Aligarh, India. He is also the Coordinator, Faculty of Agricultural Sciences, AMU for the BSc (Hons) Agriculture course. He has extensive teaching and research experience in applied & interdisciplinary microbiology and medicinal plant-derived natural products. His present research interest is in the field of AMR in pathogenic bacteria of environmental and clinical origin and conducting research on interference of quorum sensing-linked virulence factors and biofilms by natural products including medicinal plants as a possible alternative strategy to combat MDR. Dr. Ahmad has published more than 150 original research papers, 10 edited books, and 50 book chapters. In addition, he serves as an active reviewer/member of the editorial board for many prominent research journals.
Prof (Dr.) Kendra P. Rumbaugh
Kendra Rumbaugh is a Professor at the Department of Surgery, with joint appointments at the Departments of Immunology and Molecular Microbiology and Cell Biology and Biochemistry at Texas Tech University Health Sciences Center in Lubbock, Texas. Dr. Rumbaugh’s research focuses on understanding and treating wound infections, and she is especially interested in how biofilms, polymicrobial interactions and quorum sensing contribute to bacterial pathogenesis. She has edited books on quorum sensing (Springer) and antibiofilm agents (Springer), and serves on many international science advisory boards, program committees and the editorial boards of many high ranked journals.
Prof (Dr.) Shamim Ahmad
Shamim Ahmad is a senior Professor of Ocular Microbiology at the Institute of Ophthalmology, JN Medical College, Faculty of Medicine, Aligarh Muslim University, Aligarh, India. He has also served as faculty on deputation from AMUAligarh at the Department of Clinical Microbiology, Al-Arab Medical University, Libya and at the Department of Medical Microbiology, College of Medicine, Faculty of Medicine, King Khalid University, Saudi Arabia. Prof. Ahmad has been a recipient of at least 6 International Fellowships including DAAD (Germany), JSPS (Japan), ROYAL SOC. London (UK), TUBA (Turkey) and SAIA (Slovak Republic) as a Visiting Professor, mostly sponsored by the Govt. of India. Having worked at seven laboratories around the world, his research work mainly involves Multi Resistant Eye Pathogens including Super Bugs, MRSAs and their alternative treatment with newer antibacterial and innovative natural products. Prof. Ahmad serves on the editorial boards of many prominent research journals.
Bibliographic Information
Book Title: Antibacterial Drug Discovery to Combat MDR
Book Subtitle: Natural Compounds, Nanotechnology and Novel Synthetic Sources
Editors: Iqbal Ahmad, Shamim Ahmad, Kendra P. Rumbaugh
DOI: https://doi.org/10.1007/978-981-13-9871-1
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-9870-4Published: 20 November 2019
Softcover ISBN: 978-981-13-9873-5Published: 20 November 2020
eBook ISBN: 978-981-13-9871-1Published: 09 November 2019
Edition Number: 1
Number of Pages: XII, 680
Number of Illustrations: 32 b/w illustrations, 31 illustrations in colour
Topics: Medical Microbiology, Pharmacology/Toxicology, Infectious Diseases, Bacteriology, Nanotechnology