Overview
Examines the utility of GWAS in a range of common diseases
Identifies limitations and means of overcoming them
Offers guidance on recruitment of samples and data analysis
Looks to the future of GWAS and what lies beyond
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Table of contents (8 chapters)
Keywords
About this book
This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.
Editors and Affiliations
About the editors
Toshihiro Tanaka, BioResource Research Center, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510 Tokyo, 13 Japan
Yusuke Nakamura, Dept. of Medicine, University of Chicago, 900 E. 57th Street, 6240G, 60637 Chicago, IL, USA
Bibliographic Information
Book Title: Genome-Wide Association Studies
Editors: Tatsuhiko Tsunoda, Toshihiro Tanaka, Yusuke Nakamura
DOI: https://doi.org/10.1007/978-981-13-8177-5
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-8176-8Published: 14 November 2019
Softcover ISBN: 978-981-13-8179-9Published: 14 November 2020
eBook ISBN: 978-981-13-8177-5Published: 31 October 2019
Edition Number: 1
Number of Pages: IX, 209
Number of Illustrations: 2 b/w illustrations, 7 illustrations in colour
Topics: Human Genetics, Cancer Research, Immunology