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  • Reference work
  • © 2021

Liposome-Based Drug Delivery Systems

  • Offers deep coverage on all aspects of biomaterials science
  • Includes a collection of golden experimental procedures to illustrate the different fundamental concepts
  • Provides an essential source for academics and practitioners

Part of the book series: Biomaterial Engineering (BIOENG)

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Table of contents (29 entries)

  1. Front Matter

    Pages i-xx
  2. General Protocols for Fabrication of Drug Liposomes

    1. Front Matter

      Pages 1-1
    2. Liposomes in Drug Delivery: Status and Advances

      • Ying-Jie Hu, Rui-Jun Ju, Fan Zeng, Xian-Rong Qi, Wan-Liang Lu
      Pages 3-24
    3. Preparation of Drug Liposomes by Reverse-Phase Evaporation

      • Nian-Qiu Shi, Xian-Rong Qi
      Pages 37-46
    4. Preparation and Characterization of Drug Liposomes by pH-Gradient Method

      • Nian-Qiu Shi, Xian-Rong Qi, Bai Xiang
      Pages 47-58
    5. Preparation of Drug Liposomes by EDTA Gradient Methods

      • Yanzhi Song, Yihui Deng
      Pages 79-95
    6. Purification Method of Drug-Loaded Liposome

      • Meng Lin, Xian-Rong Qi
      Pages 111-121
    7. Quality Evaluation of Drug-Loaded Liposomes

      • Meng Lin, Rudong Wang, Xian-Rong Qi
      Pages 123-140
  3. Functionalized Liposome-Based Drug Delivery Systems and Potential Application

    1. Front Matter

      Pages 141-141
    2. Coupling Methods of Antibodies and Ligands for Liposomes

      • Ming Chen, Qiu-Ran Ma, Wan-Liang Lu
      Pages 143-166
    3. Preparation and Characterization of DNA Liposomes Vaccine

      • Ya-Fei Du, Ming Chen, Jia-Rui Xu, Qian Luo, Wan-Liang Lu
      Pages 259-275
    4. Preparation and Evaluation of Biomineral-Binding Antibiotic Liposomes

      • Xin-Ming Liu, Ke Ren, Geoffrey Wu, Dong Wang
      Pages 277-292

About this book

This volume describes the protocols for fabrication of liposomal drug delivery system, and consists of two parts. The first part emphasizes the basic protocols and concepts for fabrication of drug-loaded liposomes. For new investigators, laying the groundwork is the first step. This part focuses on the fabrication details in liposomes formulations, which are the so-called small tricks while usually not disclosed in mostly published research articles. However, these processing details are crucial for the preparation of liposomes. And the second part focuses on the strategies in modified and/or functionalized liposomes to adapt to pathophysiological environment, as well as their application in treating diseases. As new analytical and synthetic technologies become available, and improved understanding of pathophysiology, various functionalized drug liposomes are developing to fit the requirements of different therapeutic purposes, exhibiting a broad range of applications. Accordingly,the objectives of this part are aimed at deeply unearthing the formulation of drug-loaded liposomes, describing the detailed operation of liposomal formulation, and further demonstrating their potential applications. Therefore, this volume shows the features of experimental report or protocol for proving a guide to scientists, research students, and young investigators in pharmaceutical enterprises.


Editors and Affiliations

  • Beijing Key Laboratory of Molecular Pharmaceutics and New Drug System, Beijing, China

    Wan-Liang Lu

  • Department of Pharmaceutics School of Pharmaceutical Science, Peking University, Beijing, China

    Xian-Rong Qi

About the editors

Prof. Dr. Wan-Liang Lu a principal investigator in State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Systems, and School of Pharmaceutical Sciences, Peking University, Beijing, China

Prof. Dr. Xian-Rong Qi  a principal investigator in Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Systems, Department of Pharmaceutics, and School of Pharmaceutical Sciences, Peking University, Beijing, China

Bibliographic Information