Advances in Experimental Medicine and Biology

Protein Targeting Compounds

Prediction, Selection and Activity of Specific Inhibitors

Editors: Böldicke, Thomas (Ed.)

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  • A comprehensive overview of strategies for the generation of protein inhibitors
  • Covering prediction, selection and the biological application of protein inhibitors
  • Extensive discussion of future approaches and applications of protein inhibitors
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eBook 128,39 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-32805-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 159,99 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-32804-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover 159,99 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-81373-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions.

Key aspects of this book are:

- Selection strategies for monoclonal and recombinant human antibodies

- Selection strategies for ER intrabodies, peptides and aptamers

- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology

- Antibodies for cancer therapy and inhibitors of angiogenesis.

The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook 128,39 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-32805-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover 159,99 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-32804-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover 159,99 €
price for China (P.R.) (gross)
  • ISBN 978-3-319-81373-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Protein Targeting Compounds
Book Subtitle
Prediction, Selection and Activity of Specific Inhibitors
Editors
  • Thomas Böldicke
Series Title
Advances in Experimental Medicine and Biology
Series Volume
917
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-32805-8
DOI
10.1007/978-3-319-32805-8
Hardcover ISBN
978-3-319-32804-1
Softcover ISBN
978-3-319-81373-8
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 288
Number of Illustrations
18 b/w illustrations, 31 illustrations in colour
Topics