Reviews on Biomarker Studies in Aging and Anti-Aging Research

1. Front Matter

   Pages i-viii

   PDF

2. Of Mice, Whales, Jellyfish and Men: In Pursuit of Increased Longevity

   • Paul C. Guest

   Pages 1-24

3. Effects on Glial Cell Glycolysis in Schizophrenia: An Advanced Aging Phenotype?

   • Giuliana S. Zuccoli, Paul C. Guest, Daniel Martins-de-Souza

   Pages 25-38

4. Aging Biomarkers and Novel Targets for Anti-Aging Interventions

   • Kang Xu, Yannan Guo, Zhongchi Li, Zhao Wang

   Pages 39-56

5. Sex Differences in Aging and Associated Biomarkers

   • Natalie Thomas, Caroline Gurvich, Jayashri Kulkarni

   Pages 57-76

6. The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders

   • Ann-Katrin Kraeuter, Paul C. Guest, Zoltan Sarnyai

   Pages 77-101

7. Coenzyme Q10 Supplementation in Fibrosis and Aging

   • Iain P. Hargreaves, David Mantle

   Pages 103-112

8. Dietary Restriction, Cardiovascular Aging and Age-Related Cardiovascular Diseases: A Review of the Evidence

   • Behnaz Abiri, Mohammadreza Vafa

   Pages 113-127

9. Gut Microbiota and Microbiota-Related Metabolites as Possible Biomarkers of Cognitive Aging

   • Andrea Ticinesi, Antonio Nouvenne, Claudio Tana, Beatrice Prati, Tiziana Meschi

   Pages 129-154

10. The Impact of Herbal Products in the Prevention, Regeneration and Delay of Skin Aging

    • Mega Ferdina Warsito, Idha Kusumawati

    Pages 155-174

11. Epigenetic Clock: Just a Convenient Marker or an Active Driver of Aging?

    • Vasily V. Ashapkin, Lyudmila I. Kutueva, Boris F. Vanyushin

    Pages 175-206

12. From White to Brown – Adipose Tissue Is Critical to the Extended Lifespan and Healthspan of Growth Hormone Mutant Mice

    • Justin Darcy, Andrzej Bartke

    Pages 207-225

13. The Cytoskeleton as a Modulator of Aging and Neurodegeneration

    • Konstantinos Kounakis, Nektarios Tavernarakis

    Pages 227-245

14. Metabolic Biomarkers in Aging and Anti-Aging Research

    • Paul C. Guest

    Pages 247-264

15. Back Matter

    Pages 265-274

    PDF

Using both epidemiological and model organism approaches, we have gained new insights into the physiological and molecular aspects of aging, which has led to significant advancements in potential anti-aging strategies. Reviews on Biomarker Studies in Aging and Anti-Aging Research presents a series of reviews in various aspects of aging and age-related disease research along with several methods which have shown progress as potential anti-aging approaches. The book is aimed at researchers in the areas of aging and chronic disease, as well as to clinical scientists, physicians and major drug companies. It provides important information on disease mechanisms, and each chapter is presented in the context of the aging process, specific chronic diseases or different therapeutic areas.

• circadian interactions
• ketone diet
• brown fat
• mefomin administration
• mitophagy
• glycolysis
• Proteomics
• Systems Biology

• Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

  Paul C. Guest

Dr Paul C. Guest, Ph.D, is a scientific researcher/writer with 35 years of experience in the fields of metabolic and neurological disorders. This includes experience in both academia and the pharmaceutical industry with the majority of time spent at the University of Cambridge and Merck Sharp & Dohme in the United Kingdom. He has also been affiliated with the University of Campinas in Sao Paulo Brazil since 2015, still focused on advancing the field of biomarkers for neurological disorders such as schizophrenia and Alzheimer’s disease.

Policies and ethics