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The Drosophila Model in Cancer

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  • © 2019

Overview

  • Reviews use of the powerful Drosophila model for cancer studies from gene discovery to models of disease progression, to drug screening.
  • Highlights the challenges in cancer research and how the humble fruit-fly model can help
  • Offers guidance for researchers to develop new models, concepts and therapeutic strategies against cancer

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1167)

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Table of contents (15 chapters)

Keywords

About this book

This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics.  Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression.

 

Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use.  This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems.

 

This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.

Editors and Affiliations

  • Department of Biochemistry and Molecular Biology, Tulane Cancer Center, LCRC, Tulane University School of Medicine, New Orleans, USA

    Wu-Min Deng

About the editor

Wu-Min Deng is a Professor at the Department of Biological Sciences in Florida State University.

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