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Drug Delivery Systems

  • Book
  • © 2020

Overview

Editors:
  1. Kewal K. Jain

    1. Jain PharmaBiotech, Basel, Switzerland

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2059)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. An Overview of Drug Delivery Systems

    • Kewal K. Jain
    Pages 1-54

  3. Role of Nanobiotechnology in Drug Delivery

    • Kewal K. Jain
    Pages 55-73

  4. Intrathecal Drug Delivery

    • José De Andrés, Rubén Rubio-Haro, Carmen De Andres-Serrano, Juan Marcos Asensio-Samper, Gustavo Fabregat-Cid
    Pages 75-108

  5. Microanatomy Relevant to Intrathecal Drug Delivery

    • Miguel Angel Reina, André Boezaart, Carmen De Andres-Serrano, Rubén Rubio-Haro, José De Andrés
    Pages 109-120

  6. Drug Delivery Applications of Nanoparticles in the Spine

    • Indu Venugopal, Ankit I. Mehta, Andreas A. Linninger
    Pages 121-143

  7. Synthesis of Gold Nanoparticle: Peptide–Drug Conjugates for Targeted Drug Delivery

    • K. Kalishwaralal, G. Luboshits, M. A. Firer
    Pages 145-154

  8. A Method for Targeted Nonviral siRNA Delivery in Cancer and Inflammatory Diseases

    • Rima Kandil, Yuran Xie, Aditi Mehta, Olivia Merkel
    Pages 155-166

  9. Tumor-Targeted Dendrimer Nanoparticles for Combinatorial Delivery of siRNA and Chemotherapy for Cancer Treatment

    • Narsireddy Amreddy, Rebaz A. Ahmed, Anupama Munshi, Rajagopal Ramesh
    Pages 167-189

  10. Sonoporation for Augmenting Chemotherapy of Pancreatic Ductal Adenocarcinoma

    • Jason Castle, Spiros Kotopoulis, Flemming Forsberg
    Pages 191-205

  11. Preparation of Cholera Toxin Subunit B Functionalized Nanoparticles for Targeted Therapy of Glioblastoma

    • Juan Guan, Jun Qian, Changyou Zhan
    Pages 207-212

  12. Microfluidic Manufacturing of Multitargeted PLGA/PEG Nanoparticles for Delivery of Taxane Chemotherapeutics

    • Cláudia Martins, Bruno Sarmento
    Pages 213-224

  13. Computer-Aided Design of Nanoparticles for Transdermal Drug Delivery

    • Rakesh Gupta, Beena Rai
    Pages 225-237

  14. Microneedle-Mediated Transdermal Delivery of Tizanidine Hydrochloride

    • Hetal Thakkar, Kartik Pandya, Brijesh Patel
    Pages 239-258

  15. Targeted siRNA Delivery Using Lipid Nanoparticles

    • Andreia Jorge, Alberto Pais, Carla Vitorino
    Pages 259-283

  16. Lipid Nanocarriers for Enhanced Delivery of Temozolomide to the Brain

    • Archana Khosa, Kowthavarapu V. Krishna, Sunil Kumar Dubey, Ranendra Narayan Saha
    Pages 285-298

  17. Construction of a Macrophage-Targeting Bio-nanocapsule-Based Nanocarrier

    • Hao Li, Masaharu Somiya, Kenji Tatematsu, Shun’ichi Kuroda
    Pages 299-313

  18. Back Matter

    Pages 315-316
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Keywords

About this book

This third edition volume expands on the previous editions with a discussion of new and updated methods used to study drug delivery. Chapters cover topics such as drug delivery in cancer and intrathecal delivery of analgesics in humans. The increasing role of nanobiotechnology is reflected in eight of the sixteen chapters that include synthesis of gold nanoparticles; targeted siRNA delivery; and lipid nanocarriers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and thorough, Drug Delivery Systems: Methods and Protocols, Third Edition is a valuable resource for scientists working in industry or academia, and physicians involved in research and clinical care of patients.


Editors and Affiliations

  • Jain PharmaBiotech, Basel, Switzerland

    Kewal K. Jain

Bibliographic Information

  • Book Title: Drug Delivery Systems

  • Editors: Kewal K. Jain

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-9798-5

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2020

  • Hardcover ISBN: 978-1-4939-9797-8Published: 22 August 2019

  • Softcover ISBN: 978-1-4939-9800-5Published: 22 August 2020

  • eBook ISBN: 978-1-4939-9798-5Published: 21 August 2019

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 3

  • Number of Pages: XI, 316

  • Number of Illustrations: 18 b/w illustrations, 36 illustrations in colour

  • Topics: Biotechnology, Pharmacology/Toxicology

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