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Measuring Cerebellar Function

  • Book
  • © 2022

Overview

Editors:
  1. Roy V. Sillitoe

    1. Houston, USA

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  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Neuromethods (NM, volume 177)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Cerebellar Modelling Using Human Induced Pluripotent Stem Cells

    • Max J. van Essen, Samuel Nayler, Elizabeth J. Apsley, John Jacob, Esther B. E. Becker
    Pages 1-21

  3. From Cerebellar Genes to Behaviors in Zebrafish

    • Masahiko Hibi, Takashi Shimizu
    Pages 23-46

  4. Silencing the Output of Cerebellar Neurons Using Cell Type-Specific Genetic Deletion of Vesicular GABA and Glutamate Transporters

    • Meike E. van der Heijden, Amanda M. Brown, Roy V. Sillitoe
    Pages 47-67

  5. Mapping Structure–Function Relationships within Cerebellar Circuits

    • Richard Apps, Charlotte L. Lawrenson, Elena Paci, Nadia L. Cerminara
    Pages 69-90

  6. Designing Behavioral Tasks for Cerebellar Functional Analysis in the Mouse

    • Court Hull
    Pages 91-108

  7. Learning Paradigms and Genetic Tools for the Study of Cerebellum-Dependent Learning and Memory

    • Akira Katoh
    Pages 109-132

  8. Activity-Dependent Chromatin Mechanisms in Cerebellar Motor Learning

    • Pamela Valnegri, Tomoko Yamada, Yue Yang
    Pages 133-148

  9. In Vitro Voltage Imaging of Subthreshold Activity in Inferior Olive Neurons with ANNINE-6plus

    • Kevin Dorgans, Bernd Kuhn, Marylka Yoe Uusisaari
    Pages 149-170

  10. Mapping Synaptic Connectivity in the Cerebellar Cortex Using RuBi-Glutamate Uncaging

    • Ludovic Spaeth, Théo Gagneux, Kevin Dorgans, Antoine Valera, Izumi Sugihara, Philippe Isope
    Pages 171-185

  11. Multi-site Extracellular Electrode Neuronal Recordings in the Rodent Cerebellar Cortex and Nuclei

    • Thibault Tarpin, Victor Llobet, Guillaume Dugué, Zuzanna Piwkowska, Andrés P. Varani, Andrei Khilkevich et al.
    Pages 187-209

  12. Investigating Cerebrocerebellar Neuronal Interactions in Freely Moving Mice Using Multi-electrode, Multi-site Recordings

    • Yu Liu, Brittany L. Correia, Mia B. Fox, Detlef H. Heck
    Pages 211-227

  13. In Vivo Optical Detection of Membrane Potentials in the Cerebellum : Voltage Imaging of Zebrafish

    • Kanae Hiyoshi, Narumi Fukuda, Asuka Shiraishi, Sachiko Tsuda
    Pages 229-244

  14. Imaging Neuronal Activity in Cerebellar Cortex of Behaving Mice

    • Mikhail Kislin, Gerard Joey Broussard, Ben Deverett, Samuel S.-H Wang
    Pages 245-269

  15. Measuring Cerebellar Processing and Sensorimotor Functions in Non-Human Primates

    • Nico A. Flierman, Eric Avila, Chris I. De Zeeuw, Aleksandra Badura
    Pages 271-304

  16. Optogenetics in Complex Model Systems (Non-Human Primate)

    • Robijanto Soetedjo, Yoshiko Kojima
    Pages 305-321

  17. Clinical Assessment of the Cerebellum

    • Jason S. Gill, Jennifer Deger, Roy V. Sillitoe
    Pages 323-345

  18. Back Matter

    Pages 347-351
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Keywords

About this book

This volume considers the current techniques used by experts to study and measure cerebellar function. The chapters in this book cover topics such as stem cell-based techniques; conditional genetics approaches in model systems; neuronal recordings conducted in vitro and in vivo; and an ever-growing list of behavioral paradigms. This book also provides readers with a guide for how to use tools such as iPSCs and how to address questions using a range of approaches in animal model systems including mouse, rat, zebrafish, and non-human primate. In the Neuromethods series style, the chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Measuring Cerebellar Function is a valuable resource for cerebellar enthusiasts and other scientists interested in learning more about the cerebellum and the technological advances that are currently being employed to unlock brain function and understand animal behavior.


Editors and Affiliations

  • Houston, USA

    Roy V. Sillitoe

Bibliographic Information

  • Book Title: Measuring Cerebellar Function

  • Editors: Roy V. Sillitoe

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-0716-2026-7

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2022

  • Hardcover ISBN: 978-1-0716-2025-0Published: 06 January 2022

  • Softcover ISBN: 978-1-0716-2028-1Published: 07 January 2023

  • eBook ISBN: 978-1-0716-2026-7Published: 05 January 2022

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIII, 351

  • Number of Illustrations: 77 illustrations in colour

  • Topics: Neurosciences, Stem Cells

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