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Chemistry - Analytical Chemistry | Journal of The American Society for Mass Spectrometry

Journal of The American Society for Mass Spectrometry

Journal of The American Society for Mass Spectrometry

The official journal of The American Society for Mass Spectrometry

Editor-in-Chief: Joseph A. Loo

ISSN: 1044-0305 (print version)
ISSN: 1879-1123 (electronic version)

Journal no. 13361

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Instructions for Authors

Manuscript Submission 

Manuscript Submission

Submission of a manuscript implies: that the work described has not been published before; that it is not under consideration for publication anywhere else; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities – tacitly or explicitly – at the institute where the work has been carried out. The publisher will not be held legally responsible should there be any claims for compensation.


Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.

Online Submission

Please follow the hyperlink “Submit online” on the right and upload all of your manuscript files following the instructions given on the screen.


Resubmit manuscripts for which revisions were requested within one month of receipt of the reviews. Manuscripts received after this period may be regarded as new submissions and may be subject to re-reviewing to ensure currency.
Related Unpublished Work
Submit with the manuscript copies of any articles describing work that is related and that is submitted to or in press in any journal. These documents should be submitted as "supplementary material" via the Editorial Manager website.
Copyright Transfer, Proofs, Reprints
Return signed copyright transfer forms, which are sent separately as e-mail attachments from the publisher, acknowledging receipt of the accepted manuscript. Copyright is owned by the American Society for Mass Spectrometry, but the Publisher arranges copyright transfer. Authors receive proofs and instructions from the Publisher by e-mail and/or fax and are directed to a
URL from which a PDF proof of the paper can be obtained. Instructions for making corrections accompany the proof. Return corrected proofs to the Publisher within 48 hours of notification that proofs are available.
Order reprints by using the reprint order form that accompanies the letter from the Publisher acknowledging receipt of the accepted manuscript.
Style Guide
Use as the style guide Effective Communication of Scientific Information, 3rd Ed., Coghill, A.M. and Garson, L.R., Eds., American Chemical Society, Washington, DC, 2006. Helpful information about nomenclature and descriptions specific to mass spectrometry can be found in Mass Spec Desk Reference, 2nd Ed., by O. David Sparkman, Global View Publications, Pittsburgh, PA, 2006.


Arrange manuscript as follows: Title Page, Abstract, Text, Acknowledgments, References, Tables, Appendices, Legends for figures and schemes, Illustrations. Number pages starting with the title page as page 1 and ending with the figure-legend page. References, tables, and figure legends should be provided on separate sheets at the end of the document. Arabic numerals should be used in numbering tables and figures. All tables should have short, descriptive titles, but schemes do not usually require a title. The journal prefers that the initial submission has figures, tables, and schemes embedded in the text for ease in review and included at the end of the submission.
Prepare the manuscript in double-spaced format throughout (including the title page, abstract, text, references, tables, and legends) with page format 8.5" x 11" or A4 paper with 1" (2.54 cm) margins all around.
Wherever possible, generate all mathematical and chemical symbols, equations, and formulae as part of the manuscript text. Use fractional exponents to avoid root signs.
Short Communications and Application Notes
Submit Short Communications and Application Notes to convey, respectively, preliminary reports seeking to establish precedence or specific instrument or method innovations likely to be of interest to a cross-section of readers. Communications will be published in separate sections at the beginning of each issue. Application Notes will be published at the end of an issue. Both will, insofar as possible, receive expedited handling. They may contain up to three single-column figures or tables (up to one page, total) and up to 2300 words, including references and abstract. Space allocated to figures and tables may be replaced by text (~250 words per figure or table).
Submissions exceeding these guidelines will be treated as Regular Articles.
Critical Insights
These articles are invited submissions, and those who wish to suggest a topic should contact Dr. David Russell (russell@mail.chem.tamu.edu). These feature articles are designed to be opinion-based descriptions of a current, ideally controversial or thought-provoking, area. They are restricted to 4000 words or fewer (excluding tables and figure captions but including references), with no more than six single-column figures or tables (1.5 pages, total). Space allocated to figures and tables may be replaced by text (~250 words per figure or table).
Book and Conference Reviews
Limit book and conference reviews to 1500 words or fewer. Exceptions are the reviews of multi-volume works (which can be proportionately longer) and reviews of large conferences (e.g., the Pittsburgh Conference).
The Use of High Resolution Mass Spectral Data for Formula Confirmation
For publication of exact-mass data that are used to confirm identities of synthetic and natural products, report the uncertainty in the accurate-mass measurement used for formula verification along with the result. The acceptable uncertainty in a measurement by any analytical method must be adequate for the intended use of the data.
Evaluate the uncertainty of accurate mass measurement by any statistically valid method. Determine, for example, the precision and accuracy of replicate measurements or evaluate the performance characteristics of the mass spectrometer (see, for example, Sack, T. M., Lapp, R.
L., Gross, M. L., and Kimble, B. J. Int. J. Mass Spectrom. Ion Proc. 1984, 61, 191-213).
Consider all candidates fitting the experimentally determined value and its reported uncertainty when the result of accurate mass measurement is used for formula confirmation. Do not set fixed acceptable error limits for exact mass measurement. Consider the following when using accurate mass data.
When valence rules and candidate compositions encompassing C0-100, H3-74, O0-4, and N0-4 are considered at nominal parent m/z of 118, there are no candidate formulae within 34 ppm of each other. When the ion is of m/z 750.4 and the formulae are in the range C0-100, H25-110,
O0-15, and N0-15, there are 626 candidate formulae that are possible within 5 ppm. Thus, for a measurement at m/z 118, an error of only 34 ppm uniquely defines a particular formula, whereas at m/z 750, an error (and precision) of 0.018 ppm would be required to eliminate all extraneous possibilities.


Give the paper as short a title as possible. Submit also a running title of no more than 45 characters (including spaces).
List, at the bottom of the page, "Address reprint requests to . . . " followed by the name, exact postal address with zip code, telephone number, fax number, and e-mail address of the author to whom communications, proofs, and requests for reprints should be sent.
Provide an abstract no longer than 250 words for an Original Article, Communication, Application Note, and Account and Perspective. An abstract is not required for book reviews and letters to the editor.


Organize the text as Introduction, Experimental or Methods, Theory (if applicable), Results and Discussion, and Conclusions. Conclusion should not be a repetition of the abstract or a summary of the paper.
In the experimental section of the manuscript, all special safety considerations should be described in sufficient detail so that appropriate safety measures can be taken by those repeating the experiments.
Cite references in square brackets. Refer to illustrations and tables in numerical order in the text. Spell out, or define in parentheses, all abbreviations, even if they are commonly employed, the first time they are used in the text.
Use the nomenclature recommended by the International Union of Pure and Applied Chemistry for chemical compounds. For nomenclature of mass spectrometry, see the IUPAC rules (Todd, Journal of Pure Applied Chemistry, 1991, 63, 1541-1566). Additional suggestions for definition and style can be found in Standard Definitions of Terms Relating to Mass Spectrometry, by
Price, Journal of the American Society for Mass Spectrometry, 1991, 2, 336-346 and in
Sparkman, O.D., Mass Spec Desk Reference, 2nd Ed., Global View Publishing, Pittsburgh, PA,
Give all measurements and weights in SI units, using standard abbreviations (see IUPAC Quantities, Units and Symbols in Physical Chemistry). Non-standard abbreviations should be used sparingly and must be defined at their first appearance. Daltons (Da) or mass units (u) may be used, but amu should not be used.
Headings and Subheadings
Consult articles in recent issues
of the Journal for the recommended style for headings and subheadings.
Equations, Formulae, and Schemes
Number equations (both chemical and mathematical) consecutively with a single system of Arabic numerals in parentheses placed at the right-hand side of each equation. Number chemical structures consecutively with boldface, Arabic numerals. Designate schemes showing fragmentation pathways, chemical reactions, etc. by consecutive capital Roman numerals (schemes usually do not have titles or captions); the individual pathways within schemes can be distinguished (if necessary) with lower-case letters placed on the arrows.
Add spaces before and after mathematical symbols (e.g., +, -, =) to distinguish some of them from chemical bonds.
Type acknowledgments, including complete grant or subsidy information, at the end of the text before the references.


Identify references in the text by using Arabic numerals in brackets on the line.
Cite personal communications, manuscripts in preparation, and other unpublished data in the text in parentheses or as footnotes for that page.
Add references double-spaced starting on a separate page. Number consecutively in the order in which they are mentioned in the text. Include the titles of articles in the references. The formats are:
1. Doroshenko, V. M., Cotter, R. J.: Ideal Velocity Focusing in a Reflectron Time-of-Flight Mass Spectrometer. J. Am. Soc. Mass Spectrom. 10, 992-999 (1999)
2. Mahler, H. R., Cordes, E. H.: Biological Chemistry (2nd ed.). Harper and Row, New York (1971)
3. Anderegg, R. J.: Using Deuterium Exchange and Mass Spectrometry to Study Protein Structure. In: Burlingame, A. L., Carr, S. A. (eds.) Mass Spectrometry in the Biological Sciences, p. 85. Humana Press, Totowa, NJ, (1996)
Abbreviations of journal titles should conform to those listed in The ACS Style Guide.
Double-check references for accuracy, completeness, and duplication.
Avoid, if possible, the use of footnotes. If notes are necessary, place at the bottom of the page to be published as a column footnote, or include in parentheses in text. Do not include footnotes in the reference list.


Restrict the number of figures for a full article to eight, and to three for a communication or application note (seek permission from the editor if you require a greater number of figures). Submit figures and illustrations in electronic format as specified above ("Preparing Electronic Files"). Consider carefully whether a figure is essential and avoid submitting those that contain principally "white space." Examples are figures that contain ESI mass spectra showing the molecular ion(s) or demonstrating signal-to-noise ratio or spectra that show the appearance and disappearance of peaks. These ideas can often be communicated with a sentence in the text, or the data can be presented in a table. Remove "white space" to accentuate the object if the purpose of the figure is, for example, to show mass resolving power or peak shape rather than submitting a broad-range spectrum.
Ensure that lettering and other figure objects are of adequate size to fit one-column width (3.25"; 8.25 cm) of printed text (final lettering size, after reduction, should be at least 1.5 mm high); one-column format is the preferred publication style for JASMS. Use no more than two sizes of lettering within a figure. Label multi-part figures with lower-case letters. Remove titles and explanatory material (often used in lecture presentations) and place this material in the legend. Aim for consistent presentation of axis labels, lettering style, font sizes, etc. for all the figures in the submission. Larger, complex figures will be published in two-column format.
Multi-panel figures should be assembled into a single graphic. Avoid wasted white space. Multi-panel figures should be sized so that essential details are visible after reduction in size on the printed page.
Do not submit structures and reaction schemes or mechanisms as figures. Instead, use the guidance above for "Equations, Formulae, and Schemes."
Color: Color illustrations will be published both on-line and in the print version at no charge. Please be aware of the uncertainties of color reproduction and potential complications experienced by readers with limited color vision.
Permission to Republish Figures, Schemes, Tables
Obtain written permission from both the Publisher and the author (the latter as a courtesy) to reproduce any previously published tables, figures, or schemes, using either a letter or a permission-to-publish form of your own design. Submit completed forms or letters to the editor handling your manuscript. Specify in figure or scheme legend "reprinted from reference [ ] ] with permission of . . . (specify the publisher, using the style indicated in their permission letter".
Authors are responsible for seeking permission to republish, and they should contact the permissions department of the publisher of the material to be reprinted.


Type legends double-spaced. Use Arabic numerals and verify the order in which the illustrations occur in the text. Include identification of all abbreviations not defined in the text.


Submit with your manuscript a graphical abstract (GA) figure (drawing, structure, or reaction scheme), preferably in color, to use in the Table of Contents and in the Abstract section on the title page of the article. Cover art is often chosen from graphical abstract figures.
The figure should be in one of the following file types: .tiff, .eps, .jpg, .bmp, .doc, or .pdf. It should be 8 cm (3.15 inches) wide x 4 cm (1.57 inches) high when printed at full scale (100%), and should have high quality image and text. Please insure that the illustration maintains this aspect ratio and is still informative upon reduction.
Please supply the GA figure at 100% using the following specifications/sizes:
For .tiff:
300 dpi – halftone
600 dpi - with text
600 dpi - combine halftone and text (embedded text)
1200 dpi - bitmap (pure text and lines (b/w))
For .eps:
300/600/1200 dpi - combine embedded images and vector objects
For "rastered" images (.pdf, .doc, .bmp, .jpg), the resolution should be at least 300 dpi.


If you have any questions about the review or editorial process, contact Joyce Neff, Managing
Editor at the Journal Editorial Office:
tel: (314) 935-7464
E-mail: neff@wustl.edu


  • All tables are to be numbered using Arabic numerals.
  • Tables should always be cited in text in consecutive numerical order.
  • For each table, please supply a table caption (title) explaining the components of the table.
  • Identify any previously published material by giving the original source in the form of a reference at the end of the table caption.
  • Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body.

Artwork and Illustrations Guidelines 

Electronic Figure Submission

  • Supply all figures electronically.
  • Indicate what graphics program was used to create the artwork.
  • For vector graphics, the preferred format is EPS; for halftones, please use TIFF format. MSOffice files are also acceptable.
  • Vector graphics containing fonts must have the fonts embedded in the files.
  • Name your figure files with "Fig" and the figure number, e.g., Fig1.eps.

Line Art

Line BW
  • Definition: Black and white graphic with no shading.
  • Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size.
  • All lines should be at least 0.1 mm (0.3 pt) wide.
  • Scanned line drawings and line drawings in bitmap format should have a minimum resolution of 1200 dpi.
  • Vector graphics containing fonts must have the fonts embedded in the files.

Halftone Art

Halftone gray color
  • Definition: Photographs, drawings, or paintings with fine shading, etc.
  • If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves.
  • Halftones should have a minimum resolution of 300 dpi.

Combination Art

  • Definition: a combination of halftone and line art, e.g., halftones containing line drawing, extensive lettering, color diagrams, etc.
  • Combination artwork should have a minimum resolution of 600 dpi.

Color Art

  • Color art is free of charge for online publication.
  • If black and white will be shown in the print version, make sure that the main information will still be visible. Many colors are not distinguishable from one another when converted to black and white. A simple way to check this is to make a xerographic copy to see if the necessary distinctions between the different colors are still apparent.
  • If the figures will be printed in black and white, do not refer to color in the captions.
  • Color illustrations should be submitted as RGB (8 bits per channel).

Figure Lettering

  • To add lettering, it is best to use Helvetica or Arial (sans serif fonts).
  • Keep lettering consistently sized throughout your final-sized artwork, usually about 2–3 mm (8–12 pt).
  • Variance of type size within an illustration should be minimal, e.g., do not use 8-pt type on an axis and 20-pt type for the axis label.
  • Avoid effects such as shading, outline letters, etc.
  • Do not include titles or captions within your illustrations.

Figure Numbering

  • All figures are to be numbered using Arabic numerals.
  • Figures should always be cited in text in consecutive numerical order.
  • Figure parts should be denoted by lowercase letters (a, b, c, etc.).
  • If an appendix appears in your article and it contains one or more figures, continue the consecutive numbering of the main text. Do not number the appendix figures,
    "A1, A2, A3, etc." Figures in online appendices (Electronic Supplementary Material) should, however, be numbered separately.

Figure Captions

  • Each figure should have a concise caption describing accurately what the figure depicts. Include the captions in the text file of the manuscript, not in the figure file.
  • Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type.
  • No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption.
  • Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs.
  • Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

Figure Placement and Size

  • Figures should be submitted separately from the text, if possible.
  • When preparing your figures, size figures to fit in the column width.
  • For most journals the figures should be 39 mm, 84 mm, 129 mm, or 174 mm wide and not higher than 234 mm.
  • For books and book-sized journals, the figures should be 80 mm or 122 mm wide and not higher than 198 mm.


If you include figures that have already been published elsewhere, you must obtain permission from the copyright owner(s) for both the print and online format. Please be aware that some publishers do not grant electronic rights for free and that Springer will not be able to refund any costs that may have occurred to receive these permissions. In such cases, material from other sources should be used.


In order to give people of all abilities and disabilities access to the content of your figures, please make sure that
  • All figures have descriptive captions (blind users could then use a text-to-speech software or a text-to-Braille hardware)
  • Patterns are used instead of or in addition to colors for conveying information (colorblind users would then be able to distinguish the visual elements)
  • Any figure lettering has a contrast ratio of at least 4.5:1

Electronic Supplementary Material 

Springer accepts electronic multimedia files (animations, movies, audio, etc.) and other supplementary files to be published online along with an article or a book chapter. This feature can add dimension to the author's article, as certain information cannot be printed or is more convenient in electronic form.
Before submitting research datasets as electronic supplementary material, authors should read the journal’s Research data policy. We encourage research data to be archived in data repositories wherever possible.


  • Supply all supplementary material in standard file formats.
  • Please include in each file the following information: article title, journal name, author names; affiliation and e-mail address of the corresponding author.
  • To accommodate user downloads, please keep in mind that larger-sized files may require very long download times and that some users may experience other problems during downloading.

Audio, Video, and Animations

  • Aspect ratio: 16:9 or 4:3
  • Maximum file size: 25 GB
  • Minimum video duration: 1 sec
  • Supported file formats: avi, wmv, mp4, mov, m2p, mp2, mpg, mpeg, flv, mxf, mts, m4v, 3gp

Text and Presentations

  • Submit your material in PDF format; .doc or .ppt files are not suitable for long-term viability.
  • A collection of figures may also be combined in a PDF file.


  • Spreadsheets should be submitted as .csv or .xlsx files (MS Excel).

Specialized Formats

  • Specialized format such as .pdb (chemical), .wrl (VRML), .nb (Mathematica notebook), and .tex can also be supplied.

Collecting Multiple Files

  • It is possible to collect multiple files in a .zip or .gz file.


  • If supplying any supplementary material, the text must make specific mention of the material as a citation, similar to that of figures and tables.
  • Refer to the supplementary files as “Online Resource”, e.g., "... as shown in the animation (Online Resource 3)", “... additional data are given in Online Resource 4”.
  • Name the files consecutively, e.g. “ESM_3.mpg”, “ESM_4.pdf”.


  • For each supplementary material, please supply a concise caption describing the content of the file.

Processing of supplementary files

  • Electronic supplementary material will be published as received from the author without any conversion, editing, or reformatting.


In order to give people of all abilities and disabilities access to the content of your supplementary files, please make sure that
  • The manuscript contains a descriptive caption for each supplementary material
  • Video files do not contain anything that flashes more than three times per second (so that users prone to seizures caused by such effects are not put at risk)

English Language Editing 

For editors and reviewers to accurately assess the work presented in your manuscript you need to ensure the English language is of sufficient quality to be understood. If you need help with writing in English you should consider:
  • Asking a colleague who is a native English speaker to review your manuscript for clarity.
  • Visiting the English language tutorial which covers the common mistakes when writing in English.
  • Using a professional language editing service where editors will improve the English to ensure that your meaning is clear and identify problems that require your review. Two such services are provided by our affiliates Nature Research Editing Service and American Journal Experts. Springer authors are entitled to a 10% discount on their first submission to either of these services, simply follow the links below.
Please note that the use of a language editing service is not a requirement for publication in this journal and does not imply or guarantee that the article will be selected for peer review or accepted.
If your manuscript is accepted it will be checked by our copyeditors for spelling and formal style before publication.


● 请一位以英语为母语的同事审核您的稿件是否表意清晰。
● 查看一些有关英语写作中常见语言错误的教程。
● 使用专业语言编辑服务,编辑人员会对英语进行润色,以确保您的意思表达清晰,并识别需要您复核的问题。我们的附属机构 Nature Research Editing Service 和合作伙伴 American Journal Experts 即可提供此类服务。


・プロの英文校正サービスを利用する。校正者が原稿の意味を明確にしたり、問題点を指摘し、英語の質を向上させます。Nature Research Editing Service とAmerican Journal Experts の2つは弊社と提携しているサービスです。Springer の著者は、いずれのサービスも初めて利用する際には10%の割引を受けることができます。以下のリンクを参照ください。


영어 원고의 경우, 에디터 및 리뷰어들이 귀하의 원고에 실린 결과물을 정확하게 평가할 수 있도록, 그들이 충분히 이해할 수 있을 만한 수준으로 작성되어야 합니다. 만약 영작문과 관련하여 도움을 받기를 원하신다면 다음의 사항들을 고려하여 주십시오:
• 귀하의 원고의 표현을 명확히 해줄 영어 원어민 동료를 찾아서 리뷰를 의뢰합니다.
• 영어 튜토리얼 페이지에 방문하여 영어로 글을 쓸 때 자주하는 실수들을 확인합니다.
• 리뷰에 대비하여, 원고의 의미를 명확하게 해주고 리뷰에서 요구하는 문제점들을 식별해서 영문 수준을 향상시켜주는 전문 영문 교정 서비스를 이용합니다. Nature Research Editing Service와 American Journal Experts에서 저희와 협약을 통해 서비스를 제공하고 있습니다. Springer 저자들이 본 교정 서비스를 첫 논문 투고를 위해 사용하시는 경우 10%의 할인이 적용되며, 아래의 링크를 통하여 확인이 가능합니다.
영문 교정 서비스는 게재를 위한 요구사항은 아니며, 해당 서비스의 이용이 피어 리뷰에 논문이 선택되거나 게재가 수락되는 것을 의미하거나 보장하지 않습니다.
원고가 수락될 경우, 출판 전 저희측 편집자에 의해 원고의 철자 및 문체를 검수하는 과정을 거치게 됩니다.

Ethical Responsibilities of Authors 

This journal is committed to upholding the integrity of the scientific record. As a member of the Committee on Publication Ethics (COPE) the journal will follow the COPE guidelines on how to deal with potential acts of misconduct.
Authors should refrain from misrepresenting research results which could damage the trust in the journal, the professionalism of scientific authorship, and ultimately the entire scientific endeavour. Maintaining integrity of the research and its presentation can be achieved by following the rules of good scientific practice, which include:
  • The manuscript has not been submitted to more than one journal for simultaneous consideration.
  • The manuscript has not been published previously (partly or in full), unless the new work concerns an expansion of previous work (please provide transparency on the re-use of material to avoid the hint of text-recycling (“self-plagiarism”)).
  • A single study is not split up into several parts to increase the quantity of submissions and submitted to various journals or to one journal over time (e.g. “salami-publishing”).
  • No data have been fabricated or manipulated (including images) to support your conclusions
  • No data, text, or theories by others are presented as if they were the author’s own (“plagiarism”). Proper acknowledgements to other works must be given (this includes material that is closely copied (near verbatim), summarized and/or paraphrased), quotation marks are used for verbatim copying of material, and permissions are secured for material that is copyrighted.
    Important note: the journal may use software to screen for plagiarism.
  • Consent to submit has been received explicitly from all co-authors, as well as from the responsible authorities - tacitly or explicitly - at the institute/organization where the work has been carried out, before the work is submitted.
  • Authors whose names appear on the submission have contributed sufficiently to the scientific work and therefore share collective responsibility and accountability for the results.
  • Authors are strongly advised to ensure the correct author group, corresponding author, and order of authors at submission. Changes of authorship or in the order of authors are not accepted after acceptance of a manuscript.
  • Adding and/or deleting authors and/or changing the order of authors at revision stage may be justifiably warranted. A letter must accompany the revised manuscript to explain the reason for the change(s) and the contribution role(s) of the added and/or deleted author(s). Further documentation may be required to support your request.
  • Requests for addition or removal of authors as a result of authorship disputes after acceptance are honored after formal notification by the institute or independent body and/or when there is agreement between all authors.
  • Upon request authors should be prepared to send relevant documentation or data in order to verify the validity of the results. This could be in the form of raw data, samples, records, etc. Sensitive information in the form of confidential proprietary data is excluded.
If there is a suspicion of misconduct, the journal will carry out an investigation following the COPE guidelines. If, after investigation, the allegation seems to raise valid concerns, the accused author will be contacted and given an opportunity to address the issue. If misconduct has been established beyond reasonable doubt, this may result in the Editor-in-Chief’s implementation of the following measures, including, but not limited to:
  • If the article is still under consideration, it may be rejected and returned to the author.
  • If the article has already been published online, depending on the nature and severity of the infraction, either an erratum will be placed with the article or in severe cases complete retraction of the article will occur. The reason must be given in the published erratum or retraction note. Please note that retraction means that the paper is maintained on the platform, watermarked "retracted" and explanation for the retraction is provided in a note linked to the watermarked article.
  • The author’s institution may be informed.

After Acceptance 

Upon acceptance of your article you will receive a link to the special Author Query Application at Springer’s web page where you can sign the Copyright Transfer Statement online and indicate whether you wish to order OpenChoice and offprints.
Once the Author Query Application has been completed, your article will be processed and you will receive the proofs.

Copyright transfer

Authors will be asked to transfer copyright of the article to the Publisher (or grant the Publisher exclusive publication and dissemination rights). This will ensure the widest possible protection and dissemination of information under copyright laws.


Offprints can be ordered by the corresponding author.

Color illustrations

Publication of color illustrations is free of charge.

Proof reading

The purpose of the proof is to check for typesetting or conversion errors and the completeness and accuracy of the text, tables and figures. Substantial changes in content, e.g., new results, corrected values, title and authorship, are not allowed without the approval of the Editor.
After online publication, further changes can only be made in the form of an Erratum, which will be hyperlinked to the article.

Online First

The article will be published online after receipt of the corrected proofs. This is the official first publication citable with the DOI. After release of the printed version, the paper can also be cited by issue and page numbers.

Open Choice 

Open Choice allows you to publish open access in more than 1850 Springer Nature journals, making your research more visible and accessible immediately on publication.
  • Increased researcher engagement: Open Choice enables access by anyone with an internet connection, immediately on publication.
  • Higher visibility and impact: In Springer hybrid journals, OA articles are accessed 4 times more often on average, and cited 1.7 more times on average*.
  • Easy compliance with funder and institutional mandates: Many funders require open access publishing, and some take compliance into account when assessing future grant applications.
It is easy to find funding to support open access – please see our funding and support pages for more information.
*) Within the first three years of publication. Springer Nature hybrid journal OA impact analysis, 2018.

Copyright and license term – CC BY

Open Choice articles do not require transfer of copyright as the copyright remains with the author. In opting for open access, the author(s) agree to publish the article under the Creative Commons Attribution License.

Disclosure of potential conflicts of interest 

Authors must disclose all relationships or interests that could have direct or potential influence or impart bias on the work. Although an author may not feel there is any conflict, disclosure of relationships and interests provides a more complete and transparent process, leading to an accurate and objective assessment of the work. Awareness of a real or perceived conflicts of interest is a perspective to which the readers are entitled. This is not meant to imply that a financial relationship with an organization that sponsored the research or compensation received for consultancy work is inappropriate. Examples of potential conflicts of interests that are directly or indirectly related to the research may include but are not limited to the following:
  • Research grants from funding agencies (please give the research funder and the grant number)
  • Honoraria for speaking at symposia
  • Financial support for attending symposia
  • Financial support for educational programs
  • Employment or consultation
  • Support from a project sponsor
  • Position on advisory board or board of directors or other type of management relationships
  • Multiple affiliations
  • Financial relationships, for example equity ownership or investment interest
  • Intellectual property rights (e.g. patents, copyrights and royalties from such rights)
  • Holdings of spouse and/or children that may have financial interest in the work
In addition, interests that go beyond financial interests and compensation (non-financial interests) that may be important to readers should be disclosed. These may include but are not limited to personal relationships or competing interests directly or indirectly tied to this research, or professional interests or personal beliefs that may influence your research.
The corresponding author collects the conflict of interest disclosure forms from all authors. In author collaborations where formal agreements for representation allow it, it is sufficient for the corresponding author to sign the disclosure form on behalf of all authors. Examples of forms can be found
The corresponding author will include a summary statement in the text of the manuscript in a separate section before the reference list, that reflects what is recorded in the potential conflict of interest disclosure form(s).
See below examples of disclosures:
Funding: This study was funded by X (grant number X).
Conflict of Interest: Author A has received research grants from Company A. Author B has received a speaker honorarium from Company X and owns stock in Company Y. Author C is a member of committee Z.
If no conflict exists, the authors should state:
Conflict of Interest: The authors declare that they have no conflict of interest.

Research involving human participants and/or animals 

1) Statement of human rights

When reporting studies that involve human participants, authors should include a statement that the studies have been approved by the appropriate institutional and/or national research ethics committee and have been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
If doubt exists whether the research was conducted in accordance with the 1964 Helsinki Declaration or comparable standards, the authors must explain the reasons for their approach, and demonstrate that the independent ethics committee or institutional review board explicitly approved the doubtful aspects of the study.
The following statements should be included in the text before the References section:
Ethical approval: “All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.”
Ethical approval retrospective studies
Although retrospective studies are conducted on already available data or biological material (for which formal consent may not be needed or is difficult to obtain) ethical approval may be required dependent on the law and the national ethical guidelines of a country. Authors should check with their institution to make sure they are complying with the specific requirements of their country.

2) Statement on the welfare of animals

The welfare of animals used for research must be respected. When reporting experiments on animals, authors should indicate whether the international, national, and/or institutional guidelines for the care and use of animals have been followed, and that the studies have been approved by a research ethics committee at the institution or practice at which the studies were conducted (where such a committee exists).
For studies with animals, the following statement should be included in the text before the References section:
Ethical approval: “All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.”
If applicable (where such a committee exists): “All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.”
If articles do not contain studies with human participants or animals by any of the authors, please select one of the following statements:
“This article does not contain any studies with human participants performed by any of the authors.”
“This article does not contain any studies with animals performed by any of the authors.”
“This article does not contain any studies with human participants or animals performed by any of the authors.”

Informed consent 

All individuals have individual rights that are not to be infringed. Individual participants in studies have, for example, the right to decide what happens to the (identifiable) personal data gathered, to what they have said during a study or an interview, as well as to any photograph that was taken. Hence it is important that all participants gave their informed consent in writing prior to inclusion in the study. Identifying details (names, dates of birth, identity numbers and other information) of the participants that were studied should not be published in written descriptions, photographs, and genetic profiles unless the information is essential for scientific purposes and the participant (or parent or guardian if the participant is incapable) gave written informed consent for publication. Complete anonymity is difficult to achieve in some cases, and informed consent should be obtained if there is any doubt. For example, masking the eye region in photographs of participants is inadequate protection of anonymity. If identifying characteristics are altered to protect anonymity, such as in genetic profiles, authors should provide assurance that alterations do not distort scientific meaning.
The following statement should be included:
Informed consent: “Informed consent was obtained from all individual participants included in the study.”
If identifying information about participants is available in the article, the following statement should be included:
“Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.”

Compliance with Ethical Standards 

To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals.
Authors should include the following statements (if applicable) in a separate section entitled “Compliance with Ethical Standards” when submitting a paper:
  • Disclosure of potential conflicts of interest
  • Research involving Human Participants and/or Animals
  • Informed consent
Please note that standards could vary slightly per journal dependent on their peer review policies (i.e. single or double blind peer review) as well as per journal subject discipline. Before submitting your article check the instructions following this section carefully.
The corresponding author should be prepared to collect documentation of compliance with ethical standards and send if requested during peer review or after publication.
The Editors reserve the right to reject manuscripts that do not comply with the above-mentioned guidelines. The author will be held responsible for false statements or failure to fulfill the above-mentioned guidelines.

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    2017 Impact Factor
  • 2.869
  • Aims and Scope

    Aims and Scope


    The Journal of the American Society for Mass Spectrometry is devoted mainly to the publication of research papers covering all aspects of mass spectrometry. Papers from all fields of scientific inquiry in which mass spectrometry can play a role will be considered. These fields include chemistry, physics, geology, and environmental science as well as the biological, health, and life sciences. Contributions must not have been published elsewhere. The journal is intended to be comprehensive, and its aim is to publish papers on both fundamentals and applications of mass spectrometry. Fundamental subjects include, but are not restricted to, instrumentation principles, design, and demonstration, structures and chemical properties of gas-phase ions, studies of thermodynamic properties, ion spectroscopy, chemical kinetics, mechanisms of ionization, theory of ion fragmentation, cluster ions, potential energy surfaces, and modeling.

    Papers that report on an application should have as a principal focus the use of mass spectrometry to solve a qualitative or quantitative problem. Application subjects include, but are not limited to, structural elucidation, biopolymer sequencing, development or validation of new methodology, proteomics, and environmental and forensic measurements. Papers describing computer applications will be considered, but details and compilations of programs will not be published. Both fundamental and applications papers should report new mass spectrometry science. A report of a routine application is likely to be better suited to a journal specializing in the subject of the application. For example, a paper describing the application of mass spectrometry to the structure determination of a set of natural products may be more appropriate for a natural products or organic chemistry journal

    In addition to full papers, the journal will publish Critical Insights, Communications, Comment and Reply, Application Notes, and Accounts and Perspectives. The aims of Critical Insights are to highlight topics of current interest in a thought-provoking way, to provide insider information that is often difficult to publish in regular articles, and to provoke response and debate. Critical Insights are usually invited by the associate editor for this section, but suggestions for contributions to this section should be sent to the associate editor.

    Communications are brief descriptions (four printed pages or less) of new and significant research. Purposes include establishing priority in a new area, announcing an important discovery or development, inter alia. Communications must contain some experimental or theoretical justification for the ideas being presented. It is usually expected that a Communication will be followed by a full paper.

    Short papers may also contain commentary on articles published by others in JASMS, in which case the authors of the article being discussed will be invited to reply. Those papers will be published as "Comment" and "Reply."

    Application Notes (four printed pages) are brief descriptions of technical advances in sample handling, instrumentation, data processing, interpretation of spectra, etc., that will be of interest to some segment of the mass spectrometry community.

    Accounts and Perspectives are summaries of a body of research that is reasonably completed such that general conclusions can be drawn. The subject matter is to be of significant interest to the field of mass spectrometry. These articles may either feature the work of a single author or a team of researchers, focus on recent results of a timely subject, or bring perspective to historically important developments. This category may also include articles that describe a research philosophy, identify areas that need emphasis, or represent new directions. Although Account and Perspectives will typically be invited by the editor, proposals may be submitted in advance of preparing the article. The length of Accounts and Perspectives is to be negotiated with the editor.

    The American Society for Mass Spectrometry (ASMS) was formed in 1969 to promote and disseminate knowledge of mass spectrometry and allied topics. Membership includes over 7,500 scientists involved in research and development. Members come from academic, industrial and governmental laboratories. Their interests include advancement of techniques and instrumentation in mass spectrometry, as well as fundamental research in chemistry, geology, forensics, biological sciences and physics.


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  • Instructions for Authors

    Instructions for Authors


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