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Birkhäuser

The Grand Challenge for the Future

Vaccines for Poverty-Related Diseases from Bench to Field

  • Book
  • © 2005

Overview

Editors:
  1. Stefan H.E. Kaufmann

    1. Max Planck Institute for Infection Biology, Berlin, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Paul-Henri Lambert

    1. CMU — Centre of Vaccinology, Geneva 4, Switzerland

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Discussion of issues critical for the introduction of new vaccines
  • Highlights potential benefits for public health
  • Vaccine-related economic aspects
  • New perspective of the design of vaccination strategies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Birkhäuser Advances in Infectious Diseases (BAID)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xii
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  2. Background

    1. Economic aspects of vaccines and vaccination: a global perspective

      • Philippe P.A. Beutels
      Pages 3-20

  3. Private hand

    1. How and why vaccines are made

      • Stanley A. Plotkin, James M. Robinson
      Pages 23-36

    2. How can the industrial world help to implement new vaccines against poverty-related diseases?

      • Ole F. Olesen, Arnd Hoeveler
      Pages 37-52

  5. Bench

    1. Novel vaccination strategies

      • Maria Lattanzi, Rino Rappuoli
      Pages 77-98

    2. Design and selection of vaccine adjuvants: principles and practice

      • Carl R. Alving, Gary R. Matyas
      Pages 99-118

    3. Vaccination in the context of immunological immaturity

      • Ann M. Arvin, David B. Lewis
      Pages 119-169

  7. Clinical trials

    1. Clinical trials in developing countries: ethical issues

      • Veronica L. Tallo, Hanna M. Nohynek
      Pages 189-208

    2. Vaccine safety and adverse events: lessons learnt

      • Philippe Duclos, Adwoa D. Bentsi-Enchill, Dina Pfeifer
      Pages 209-229

    3. Sequential stages of clinical trials and overview of issues to be considered

      • John D. Clemens, R. Leon Ochiai
      Pages 231-247

    4. Practical aspects of phase 3 vaccine trials in developing countries

      • Brian Greenwood
      Pages 249-265

  9. Back Matter

    Pages 287-290
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Keywords

About this book

The most urgently needed vaccines are those against poverty-related diseases such as tuberculosis, malaria and HIV. However, there is a considerable gap between the development of a vaccine and the implementation as a useful measure for disease control. Major obstacles need to be overcome even after successful completion of the preclinical stage.

This book provides an important link between vaccine development and application under the particular conditions in developing countries.
The editors, S.H.E. Kaufmann and P.H. Lambert – one from the field of basic research and the other an expert on the side of applied vaccinology – have gathered contributions from specialists of both fields in an attempt to create a source of information that has thus far not been available.

Reviews

"The book gives a useful insight into many aspects of practical vaccinology. The recent availability of new funding through the Gates Foundation, the Global Alliance for Vaccines and Immunization, and the Vaccine Fund will open new opportunities for vaccination programmes in countries of th edeveloping world."

(Microbiology Today) 

Editors and Affiliations

  • Max Planck Institute for Infection Biology, Berlin, Germany

    Stefan H.E. Kaufmann

  • CMU — Centre of Vaccinology, Geneva 4, Switzerland

    Paul-Henri Lambert

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